Evidence map›Paper›PMID 28420055›Full record

ArticleLupus2017

Perceived stress and reported cognitive symptoms among Georgia patients with systemic lupus erythematosus.

L Plantinga, S S Lim, C B Bowling, C Drenkard

Open access · greenAbstract read
In one paragraph

Article in Lupus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

L Plantinga1 Division of Renal Medicine, Department of Medicine, Emory University, Atlanta, USA.
S S Lim3 Division of Rheumatology, Department of Medicine, Emory University, Atlanta, USA.
C B Bowling4 Birmingham/Atlanta VA Geriatrics Research and Clinical Center, Decatur, USA.
C Drenkard3 Division of Rheumatology, Department of Medicine, Emory University, Atlanta, USA.
Emory University · USAtlanta VA Medical Center · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The Georgians Organized Against Lupus (GOAL) Cohort: Advancing Health DisparitiesU01DP005119 · DP · EMORY UNIVERSITY · PI DRENKARD, CRISTINA MARTA, LIM, SUNG SAM · 2014 to 2018
$4.8M
Psychosocial Factors and Lupus Disease Progression Among African American WomenR01AR065493 · NIAMS · UNIV OF MARYLAND, COLLEGE PARK · PI CHAE, H. DAVID, LIM, SUNG SAM · 2014 to 2022
$4.2M
ACL HHS U01DP005119NCATS NIH HHS UL1 TR000454NCCDPHP CDC HHS U01 DP005119NCCDPHP CDC HHS U01 DP006488NIAMS NIH HHS R01 AR065493
6 · The paper itself

Abstract

Objective To examine associations of perceived stress with cognitive symptoms among adults with systemic lupus erythematosus (SLE). Methods Among 777 adult (≥18 years) SLE patients, the association of Perceived Stress Scale (PSS) scores with two self-reported cognitive symptoms was examined: forgetfulness (severe/moderate vs. mild/none; from the Systemic Lupus Activity Questionnaire) and difficulty concentrating (all/most vs. some/little/none of the time; from the Lupus Impact Tracker). The study used multivariable logistic regression to estimate the odds ratios (ORs) per minimal important difference (MID = 0.5*SD) of PSS score and cognitive symptoms. Results Forgetfulness and difficulty concentrating were reported by 41.7% and 29.5%, respectively. Women and those with less education and high disease activity had higher PSS scores and were more likely to report cognitive symptoms than their counterparts. With adjustment for age, race, sex, education, and disease activity, each MID increase in PSS score was associated with higher prevalence of forgetfulness (OR = 1.43, 95% CI 1.29-1.47) and difficulty concentrating (OR = 2.19, 95% CI 1.90-2.52). No substantial differences in this association by age, race, sex, or disease activity were noted. Conclusions SLE patients, particularly those with high disease activity, report a high burden of cognitive symptoms, for which stress may be a modifiable risk factor.

Indexed as

AdultCognition DisordersCross-Sectional StudiesFemaleGeorgiaHumansLogistic ModelsLupus Erythematosus, SystemicMaleMiddle AgedMultivariate AnalysisPrevalenceRisk FactorsSelf ReportSeverity of Illness IndexStress, PsychologicalAfrican-Americancognitive functionstressSystemic lupus erythematosus

Identifiers

PMID28420055
PMCPMC5494014
OpenAlexW2590589503

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.