ArticleHuman brain mapping2017
BOLD neurovascular coupling does not change significantly with normal aging.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Towards whole brain mapping of the hemodynamic response function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Article
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- Imaging of brain electric field networks with spatially resolved EEG.Research square · 2025Article
- The aging human brain exhibits reduced cerebrospinal fluid flow during sleep due to both neural and vascular factors.bioRxiv : the preprint server for biology · 2025Article
- Evaluating Models of the Ageing BOLD Response.Human brain mapping · 2024Article
- The Cerebrovascular Side of Plasticity: Microvascular Architecture across Health and Neurodegenerative and Vascular Diseases.Brain sciences · 2024Review
- Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan.Human brain mapping · 2023Article
- Resting-state fMRI signals contain spectral signatures of local hemodynamic response timing.eLife · 2023Article
- Sex modifies the relationship between age and neurovascular coupling in healthy adults.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Article
- Resting-state fMRI signals contain spectral signatures of local hemodynamic response timing.bioRxiv : the preprint server for biology · 2023Article
- Variation within the visually evoked neurovascular coupling response of the posterior cerebral artery is not influenced by age or sex.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Article
- Unimanual sensorimotor learning-A simultaneous EEG-fMRI aging study.Human brain mapping · 2022Article
- Bridging patterns of neurocognitive aging across the older adult lifespan.Neuroscience and biobehavioral reviews · 2022Review
- The temporal dedifferentiation of global brain signal fluctuations during human brain ageing.Scientific reports · 2022Article
- The scalability of common paradigms for assessment of cognitive function: A functional transcranial Doppler study.PloS one · 2022Article
- Failure to engage the temporoparietal junction/posterior superior temporal sulcus predicts impaired naturalistic social cognition in schizophrenia.Brain : a journal of neurology · 2021Article
- Vascular and haemodynamic issues of brain ageing.Pflugers Archiv : European journal of physiology · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Studies of cognitive function that compare the blood oxygenation level dependent (BOLD) signal across age groups often require the assumption that neurovascular coupling does not change with age. Tests of this assumption have produced mixed results regarding the strength of the coupling and its relative time course. Using deconvolution, we found that age does not have a significant effect on the time course of the hemodynamic impulse response function or on the slope of the BOLD versus stimulus duration relationship. These results suggest that in cognitive studies of healthy aging, group differences in BOLD activation are likely due to age-related changes in cognitive-neural interactions and information processing rather than to impairments in neurovascular coupling. Hum Brain Mapp 38:3538-3551, 2017. © 2017 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.