Evidence map›Paper›PMID 28419582›Full record

ArticleMagnetic resonance in medicine2018

Free-breathing liver fat quantification using a multiecho 3D stack-of-radial technique.

Tess Armstrong, Isabel Dregely, Alto Stemmer, Fei Han, Yutaka Natsuaki, Kyunghyun Sung, Holden H Wu

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Accelerated Free-Breathing 5D Multi-Echo Respiratory Motion-Resolved R2*, PDFF, and QSM Using Novel Composite Total Variation.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Reproducibility and quality assurance in MRI.Magma (New York, N.Y.) · 2025
    Article
  12. Article
  13. Article
  14. Improved liver fat andMagnetic resonance in medicine · 2025
    Article
  15. Free-breathing MRI techniques for fat and RMagma (New York, N.Y.) · 2024
    Review
  16. Trajectory correction enables free-running chemical shift encoded imaging for accurate cardiac proton-density fat fraction quantification at 3T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024 · on this map
    Article
  17. Article
  18. Clinical Application of Quantitative MR Imaging in Nonalcoholic Fatty Liver Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tess ArmstrongDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.ORCID http://orcid.org/0000-0002-7510-0378
Isabel DregelyDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.ORCID http://orcid.org/0000-0003-4146-7363
Alto StemmerSiemens Healthcare GmbH, Erlangen, Germany.
Fei HanDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.
Yutaka NatsuakiSiemens Healthcare, Los Angeles, California, USA.
Kyunghyun SungDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.
Holden H WuDepartment of Radiological Sciences, University of California Los Angeles, Los Angeles, California, USA.ORCID http://orcid.org/0000-0002-2585-5916

Funding

UCLA Muscular Dystrophy Core CenterP30AR057230 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SPENCER, MELISSA JAN · 2009 to 2018
$6.2M
NIAMS NIH HHS P30 AR057230
6 · The paper itself

Abstract

purposeThe diagnostic gold standard for nonalcoholic fatty liver disease is an invasive biopsy. Noninvasive Cartesian MRI fat quantification remains limited to a breath-hold (BH). In this work, a novel free-breathing 3D stack-of-radial (FB radial) liver fat quantification technique is developed and evaluated in a preliminary study.

methodsPhantoms and healthy subjects (n = 11) were imaged at 3 Tesla. The proton-density fat fraction (PDFF) determined using FB radial (with and without scan acceleration) was compared to BH single-voxel MR spectroscopy (SVS) and BH 3D Cartesian MRI using linear regression (correlation coefficient ρ and concordance coefficient ρ

resultsIn phantoms, PDFF showed significant correlation (ρ > 0.998, ρ

conclusionAccurate 3D liver fat quantification can be performed in 1 to 2 min using a novel FB radial technique. Magn Reson Med 79:370-382, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Indexed as

Image Interpretation, Computer-AssistedAdipose TissueAdultAlgorithmsCalibrationFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLiverMagnetic Resonance ImagingMaleModels, StatisticalNon-alcoholic Fatty Liver DiseasePelvisPhantoms, ImagingFree-breathing abdominal MRIgradient delay correctionliver fat quantificationnonalcoholic fatty liver diseaseradial bipolar multiecho sequence

Identifiers

PMID28419582
PMCPMC5837283

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.