SynthesisNeurosurgery2018
Seizure Outcomes in Occipital Lobe and Posterior Quadrant Epilepsy Surgery: A Systematic Review and Meta-Analysis.
Synthesis in Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Predictors of outcomes after surgery for medically intractable insular epilepsy: A systematic review and individual participant data meta-analysis.Epilepsia open · 2023Pooled it
- The bed nucleus of the stria terminalis as a neuromodulatory target for refractory epilepsy.Frontiers in network physiology · 2026Review
- Article
- Occipital lobe epilepsy surgery: treating seizures in the posterior cortex.Neurosurgical review · 2024Review
- Surgical outcomes following resection in patients with language dominant posterior quadrant epilepsy.Epilepsy & behavior reports · 2024Article
- Clinical Impacts of Stereotactic Electroencephalography on Epilepsy Surgery and Associated Issues in the Current Situation in Japan.Neurologia medico-chirurgica · 2023Article
- Bevacizumab is associated with cerebral microstructural alterations: a DTI study in high-grade glioma.Frontiers in neurology · 2023Article
- Multimodal prognostic features of seizure freedom in epilepsy surgery.Journal of neurology, neurosurgery, and psychiatry · 2022Review
- Resection of bilateral occipital lobe lesions during a single operation as a treatment for bilateral occipital lobe epilepsy.World journal of clinical cases · 2021Article
- Comparative Effectiveness of Stereotactic Electroencephalography Versus Subdural Grids in Epilepsy Surgery.Annals of neurology · 2021Article
- Adult occipital lobe epilepsy: 12-years on.Journal of neurology · 2021Article
- Brain-responsive corticothalamic stimulation in the pulvinar nucleus for the treatment of regional neocortical epilepsy: A case series.Epilepsia open · 2021Article
- Neurosurgical approaches to pediatric epilepsy: Indications, techniques, and outcomes of common surgical procedures.Seizure · 2020Review
- Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study.Disease markers · 2020Article
- Evolution of patients with surgically treated drug-resistant occipital lobe epilepsy.Surgical neurology international · 2020Review
- Getting the best outcomes from epilepsy surgery.Annals of neurology · 2018Review
- Prognostic value of ictal onset patterns in postsurgical outcome of temporal lobe epilepsy.Iranian journal of neurology · 2017Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundOccipital lobe epilepsy (OLE) is an uncommon but debilitating focal epilepsy syndrome with seizures often refractory to medical management. While surgical resection has proven a viable treatment, previous studies examining postoperative seizure freedom rates are limited by small sample size and patient heterogeneity, thus exhibiting significant variability in their results.
objectiveTo review the medical literature on OLE so as to investigate rates and predictors of both seizure freedom and visual outcomes following surgery.
methodsWe reviewed manuscripts exploring surgical resection for drug-resistant OLE published between January 1990 and June 2015 on PubMed. Seizure freedom rates were analyzed and potential predictors were evaluated with separate meta-analyses. Postoperative visual outcomes were also examined.
resultsWe identified 27 case series comprising 584 patients with greater than 1 yr of follow-up. Postoperative seizure freedom (Engel class I outcome) was observed in 65% of patients, and was significantly predicted by age less than 18 yr (odds ratio [OR] 1.54, 95% confidence interval [CI] 1.13-2.18), focal lesion on pathological analysis (OR 2.08, 95% CI 1.58-2.89), and abnormal preoperative magnetic resonance imaging (OR 3.24, 95% 2.03-6.55). Of these patients, 175 also had visual outcomes reported with 57% demonstrating some degree of visual decline following surgery. We did not find any relationship between postoperative visual and seizure outcomes.
conclusionSurgical resection for OLE is associated with favorable outcomes with nearly two-thirds of patients achieving postoperative seizure freedom. However, patients must be counseled regarding the risk of visual decline following surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.