Evidence map›Paper›PMID 28419000›Full record

ArticleExercise and sport sciences reviews2017

Exercise-Induced Autophagy in Fatty Liver Disease.

Sung Kook Chun, Sooyeon Lee, Ming-Jim Yang, Christiaan Leeuwenburgh, Jae-Sung Kim

Abstract read
In one paragraph

Article in Exercise and sport sciences reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Exercise Impacts Liver Disease: Balancing Metabolic and Immune Homeostasis.International journal of biological sciences · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
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  16. Review
  17. Article
  18. Article
  19. Article
  20. Long-term exercise prevents hepatic steatosis: a novel role of FABP1 in regulation of autophagy-lysosomal machinery.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Sung Kook Chun1Department of Surgery, and 2Department of Aging and Geriatric Research, University of Florida, Gainesville, FL.
Sooyeon Lee
Ming-Jim Yang
Christiaan Leeuwenburgh
Jae-Sung Kim

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Autophagy in liver injuryR01DK079879 · NIDDK · WASHINGTON UNIVERSITY · PI Jae-Sung Kim · 2009 to 2026
$5.0M
Mitophagy: target to improve liver function after ischemia/reperfusion injuryR01DK090115 · NIDDK · UNIVERSITY OF FLORIDA · PI KIM, JAE-SUNG, LEEUWENBURGH, CHRISTIAAN · 2012 to 2015
$1.3M
NIA NIH HHS P30 AG028740NIDDK NIH HHS R01 DK079879NIDDK NIH HHS R01 DK090115
6 · The paper itself

Abstract

Hepatic steatosis prevails each year. Autophagy is integral in mitochondrial quality control and lipid homeostasis in the liver. No pharmacological strategies are currently available to reduce hepatic steatosis, but exercise has been known to improve clinical outcomes of chronic liver disease, particularly nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that exercise may improve NAFLD through enhancing autophagy.

Indexed as

AutophagyExerciseHumansLipid MetabolismLiverMitochondria, LiverMuscle, SkeletalNon-alcoholic Fatty Liver Disease

Identifiers

PMID28419000
PMCPMC5479347

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.