Evidence map›Paper›PMID 28418689›Full record

ArticleAnnals of the American Thoracic Society2017

An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness.

Eleanor M Summerhill, Gary W Hoyle, Sven-Eric Jordt, Bronwen J Jugg, James G Martin, Sadis Matalon, Steven E Patterson, David J Prezant, Alfred M Sciuto, Erik R Svendsen and 3 more

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. The long road to Ithaca: a physiologist's journey.American journal of physiology. Cell physiology · 2025
    Review
  6. Article
  7. Article
  8. Hemopexin reverses activation of lung eIF2α and decreases mitochondrial injury in chlorine-exposed mice.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Lung Regeneration: Cells, Models, and Mechanisms.Cold Spring Harbor perspectives in biology · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Circulating and tissue biomarkers as predictors of bromine gas inhalation.Annals of the New York Academy of Sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Eleanor M Summerhill
Gary W Hoyle
Sven-Eric Jordt
Bronwen J Jugg
James G Martin
Sadis Matalon
Steven E Patterson
David J Prezant
Alfred M Sciuto
Erik R Svendsen
Carl W White
Livia A Veress
ATS Terrorism and Inhalational Disasters Section of the Environmental, Occupational, and Population Health Assembly

Funding

Thiols in sulfur mustard toxicityU54ES015678 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI WHITE, CARL W · 2006 to 2015
$20.5M
Photonics Monitoring and Modeling CoreU54ES027698 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI WHITE, CARL W · 2016 to 2021
$16.7M
Targeting Injury Pathways to Counteract Pulmonary Agent and Vesicant ToxicityU01ES015674 · NIEHS · YALE UNIVERSITY · PI JORDT, SVEN-ERIC · 2006 to 2016
$6.0M
Countermeasures Against Chemical Threats: Countermeasures Against CyanideU01NS058087 · NINDS · UNIVERSITY OF MINNESOTA · PI PATTERSON, STEVEN E · 2006 to 2014
$5.6M
Novel Therapies for Chlorine-Induced Lung InjuryU01ES015673 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HOYLE, GARY W. · 2006 to 2015
$4.6M
Bromine Inhalation Induced Lung Injury: Novel Mechanisms and Treatment StrategiesU01ES026458 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MATALON, SADIS · 2015 to 2019
$3.9M
CIALIS® reverses halogen induced injury to pregnant animals and their offspringU01ES027697 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JILLING, TAMAS SANDOR, MATALON, SADIS · 2016 to 2020
$3.7M
Long-Term Lung Health After Exposure to Chlorine GasR01ES015532 · NIEHS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SVENDSEN, ERIK ROBERT · 2010 to 2014
$2.7M
Countermeasures for chlorine-induced airway fibrosisU01ES022564 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HOYLE, GARY W. · 2012 to 2016
$1.9M
Accelerating Inflammation Resolution to CounterACT Chemical InjuryR21ES022875 · NIEHS · YALE UNIVERSITY · PI JORDT, SVEN-ERIC · 2012 to 2013
$786k
Atropine for chlorine inhalation toxicityR21ES026830 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI VERESS, LIVIA AGNES · 2015 to 2016
$668k
NIEHS NIH HHS R01 ES015532NIEHS NIH HHS R21 ES022875NIEHS NIH HHS R21 ES026830NIEHS NIH HHS U01 ES015673NIEHS NIH HHS U01 ES015674NIEHS NIH HHS U01 ES022564NIEHS NIH HHS U01 ES026458NIEHS NIH HHS U01 ES027697NIEHS NIH HHS U54 ES015678NIEHS NIH HHS U54 ES027698NINDS NIH HHS U01 NS058087
6 · The paper itself

Abstract

This report is based on the proceedings from the Inhalational Lung Injury Workshop jointly sponsored by the American Thoracic Society (ATS) and the National Institutes of Health (NIH) Countermeasures Against Chemical Threats (CounterACT) program on May 21, 2013, in Philadelphia, Pennsylvania. The CounterACT program facilitates research leading to the development of new and improved medical countermeasures for chemical threat agents. The workshop was initiated by the Terrorism and Inhalational Disasters Section of the Environmental, Occupational, and Population Health Assembly of the ATS. Participants included both domestic and international experts in the field, as well as representatives from U.S. governmental funding agencies. The meeting objectives were to (1) provide a forum to review the evidence supporting current standard medical therapies, (2) present updates on our understanding of the epidemiology and underlying pathophysiology of inhalational lung injuries, (3) discuss innovative investigative approaches to further delineating mechanisms of lung injury and identifying new specific therapeutic targets, (4) present promising novel medical countermeasures, (5) facilitate collaborative research efforts, and (6) identify challenges and future directions in the ongoing development, manufacture, and distribution of effective and specific medical countermeasures. Specific inhalational toxins discussed included irritants/pulmonary toxicants (chlorine gas, bromine, and phosgene), vesicants (sulfur mustard), chemical asphyxiants (cyanide), particulates (World Trade Center dust), and respirable nerve agents.

Indexed as

Accidents, OccupationalDisaster PlanningDisastersAnimalsChemical TerrorismEnvironmental ExposureHumansLungLung InjuryModels, AnimalSocieties, MedicalUnited States

Identifiers

PMID28418689
PMCPMC5529138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.