Evidence map›Paper›PMID 28418333›Full record

ArticleeLife2017

Nonlinear feedback drives homeostatic plasticity in H

Youlian Goulev, Sandrine Morlot, Audrey Matifas, Bo Huang, Mikael Molin, Michel B Toledano, Gilles Charvin

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Review
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  6. Phenotypic consequences of logarithmic signaling in MAPK stress response.bioRxiv : the preprint server for biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Youlian GoulevDevelopmental Biology and Stem Cells Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg, France.ORCID 0000-0003-0370-4567
Sandrine MorlotDevelopmental Biology and Stem Cells Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Audrey MatifasDevelopmental Biology and Stem Cells Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Bo HuangOxidative Stress and Cancer, IBITECS, SBIGEM, CEA-Saclay, Gif-sur-Yvette, France.ORCID 0000-0001-5945-7601
Mikael MolinDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Michel B ToledanoOxidative Stress and Cancer, IBITECS, SBIGEM, CEA-Saclay, Gif-sur-Yvette, France.
Gilles CharvinDevelopmental Biology and Stem Cells Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg, France.ORCID 0000-0002-6852-6952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homeostatic systems that rely on genetic regulatory networks are intrinsically limited by the transcriptional response time, which may restrict a cell's ability to adapt to unanticipated environmental challenges. To bypass this limitation, cells have evolved mechanisms whereby exposure to mild stress increases their resistance to subsequent threats. However, the mechanisms responsible for such

Indexed as

FeedbackOxidative StressStress, PhysiologicalHydrogen PeroxideIntravital MicroscopyMicrofluidicsOptical ImagingOxidantsSaccharomyces cerevisiaeHydrogen PeroxideOxidantsacquired stress resistanceadaptationcell biologycomputational biologyH2O2 homeostasishormesisnonlinear feedbackS. cerevisiaesystems biology

Identifiers

PMID28418333
PMCPMC5438251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.