Evidence map›Paper›PMID 28418274›Full record

ArticleJournal of toxicology and environmental health. Part A2017

The Gulf Long-Term Follow-Up Study (GuLF STUDY): Biospecimen collection at enrollment.

Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Matthew D Curry, John A McGrath, Dale P Sandler

Abstract read
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Reliability of low mass toenail samples as biomarkers of chronic metal exposure.Journal of exposure science & environmental epidemiology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Natural hazards and mental health among US Gulf Coast residents.Journal of exposure science & environmental epidemiology · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Lung function in oil spill responders 4-6 years after the Deepwater Horizon disaster.Journal of toxicology and environmental health. Part A · 2020
    Article
  14. Determinants of environmental styrene exposure in Gulf coast residents.Journal of exposure science & environmental epidemiology · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lawrence S Engela Department of Epidemiology , Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.
Richard K Kwokb National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services , Research Triangle Park , NC , USA.
Aubrey K Millerb National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services , Research Triangle Park , NC , USA.
Aaron Blairc Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Department of Health and Human Services , Bethesda , MD , USA.
Matthew D Curryd Social & Scientific Systems, Inc ., Durham , NC , USA.
John A McGrathd Social & Scientific Systems, Inc ., Durham , NC , USA.
Dale P Sandlerb National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services , Research Triangle Park , NC , USA.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Gulf Longitudinal Follow-up (GuLF) Worker StudyZIAES102945 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2010 to 2025
$15.3M
Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES102945NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

The 2010 Deepwater Horizon (DWH) explosion in the Gulf of Mexico led to the largest ever marine oil spill by volume. The GuLF STUDY is investigating possible adverse human health effects associated with oil spill activities. One objective of the study was to utilize biological specimens from study participants to examine spill-related adverse health effects. This study describes the methods for collecting, processing, shipping, and storing specimens during the enrollment phase of the study. GuLF STUDY participants living in Gulf States (Alabama, Florida, Louisiana, Mississippi, and eastern Texas) were eligible to complete a home visit at enrollment, one to three years after the DWH explosion. During this visit, blood, urine, toenail and hair clippings, and house dust samples were collected. Specimens were shipped overnight to a central processing laboratory in containers with cold and ambient temperature compartments. Most blood and urine specimens were then aliquoted and stored in liquid nitrogen vapor or at -80°C, with some samples stored at -20°C. A total of 11,193 participants completed a home visit, and over 99% provided at least one biospecimen. Most participants provided blood (93%), urine (99%), and toenail clippings (89%), and 40% provided hair. Nearly all participants (95%) provided house-dust samples. Most samples were received by the laboratory one (58%) or two (25%) days after collection. These biospecimens enable investigation of a range of biomarkers of spill-related adverse health effects, and possibly some biomarkers of spill-related exposures. The biospecimen collection, handling, and storage protocols were designed to maximize current and future scientific value within logistical and budgetary constraints and might serve as a template for future studies conducted in similar time-critical and geographically dispersed settings.

Indexed as

Occupational ExposureAdultAgedAged, 80 and overEnvironmental MonitoringFemaleFollow-Up StudiesGulf of AmericaHumansMaleMiddle AgedPetroleum PollutionSoutheastern United StatesSpecimen HandlingTexasYoung Adult

Identifiers

PMID28418274
PMCPMC5522735

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.