Evidence map›Paper›PMID 28418026›Full record

ArticleScientific reports2017

The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1.

Francesca Mattiroli, Yajie Gu, Jeremy L Balsbaugh, Natalie G Ahn, Karolin Luger

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francesca MattiroliHoward Hughes Medical Institute, University of Colorado Boulder, Department of Chemistry and Biochemistry, Boulder, CO 80303, USA.
Yajie GuUniversity of Colorado at Boulder, Department of Chemistry and Biochemistry, Boulder, CO 80303, USA.
Jeremy L BalsbaughUniversity of Colorado at Boulder, Department of Chemistry and Biochemistry, Boulder, CO 80303, USA.
Natalie G AhnUniversity of Colorado at Boulder, Biofrontiers Institute, Department of Chemistry and Biochemistry, Boulder, CO 80303, USA.
Karolin LugerHoward Hughes Medical Institute, University of Colorado Boulder, Department of Chemistry and Biochemistry, Boulder, CO 80303, USA.
University of Colorado Boulder · US

Funding

Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
Structure and Function of Nucleosome Assembly Protein 1R01GM067777 · NIGMS · UNIVERSITY OF COLORADO · PI LUGER, KAROLIN · 2003 to 2015
$3.7M
Linking Dynamics to Catalysis and Inhibition in ERK2R01GM114594 · NIGMS · UNIVERSITY OF COLORADO · PI AHN, NATALIE G. · 2016 to 2019
$1.3M
ABI Elite ESI-QqTOF Mass Spectrometry SystemS10RR026641 · NCRR · UNIVERSITY OF COLORADO · PI AHN, NATALIE G. · 2010 to 2010
$458k
Howard Hughes Medical InstituteNCRR NIH HHS S10 RR026641NIGMS NIH HHS P41 GM103622NIGMS NIH HHS R01 GM067777NIGMS NIH HHS R01 GM114594
6 · The paper itself

Abstract

Nucleosome assembly following DNA replication controls epigenome maintenance and genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone responsible for histone (H3-H4)

Indexed as

Protein Interaction Domains and MotifsAmino Acid SequenceChromatinChromatin Assembly and DisassemblyChromatin Assembly Factor-1Fungal ProteinsHistonesModels, BiologicalModels, MolecularMultiprotein ComplexesNucleosomesProtein BindingProtein BiosynthesisProtein ConformationStructure-Activity RelationshipChromatinChromatin Assembly Factor-1Fungal ProteinsHistonesMultiprotein ComplexesNucleosomes

Identifiers

PMID28418026
PMCPMC5394680
OpenAlexW2605910596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.