Evidence map›Paper›PMID 28417914›Full record

Trial reportNutrients2017

Interactions of the Insulin-Like Growth Factor Axis and Vitamin D in Prostate Cancer Risk in the Prostate Cancer Prevention Trial.

Fayth L Miles, Phyllis J Goodman, Catherine Tangen, Kathleen C Torkko, Jeannette M Schenk, Xiaoling Song, Michael Pollak, Ian M Thompson, Marian L Neuhouser

Open access · goldAbstract readClinical Trial, Phase IIIRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. The double disparity: Vitamin D deficiency and lethal prostate cancer in black men.The Journal of steroid biochemistry and molecular biology · 2025
    Review
  2. Review
  3. Article
  4. Vitamin D deficiency: a potential risk factor for cancer in obesity?International journal of obesity (2005) · 2022
    Review
  5. Review
  6. Influence of Diet and Nutrition on Prostate Cancer.International journal of molecular sciences · 2020
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Fayth L MilesDepartment of Health Services, University of Washington, Seattle, WA 98105, USA. fmiles@fredhutch.org.
Phyllis J GoodmanCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. pgoodman@fredhutch.org.
Catherine TangenCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. ctangen@fredhutch.org.
Kathleen C TorkkoDepartment of Pathology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA. ktorkko@ucdenver.edu.
Jeannette M SchenkCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. jschenk@fredhutch.org.
Xiaoling SongCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. xsong2@scharp.org.
Michael PollakDepartments of Medicine and Oncology, McGill University, Montreal, QC H3A 0G4, Canada. michael.pollak@mcgill.ca.
Ian M ThompsonCancer Therapy and Research Center, University of Texas Health Science Center, San Antonio, TX 78229, USA. ThompsonI@uthscsa.edu.
Marian L NeuhouserCancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. mneuhous@fredhutch.org.
Fred Hutch Cancer Center · USMcGill University · CAThe University of Texas Health Science Center at San Antonio · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Washington · US

Funding

SWOG Foreign AccrualsU10CA037429 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BLANKE, CHARLES D., MEYSKENS, FRANK L. · 1985 to 2014
$205.2M
University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
SWOG NCORP Research BaseUG1CA189974 · NCI · THE HOPE FOUNDATION · PI CHARLES D. BLANKE, DAWN HERSHMAN · 2014 to 2026
$80.6M
Oxidative Damage and DNA Repair in the PCPTP01CA108964 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIPPMAN, SCOTT M · 2005 to 2009
$13.6M
Biobehavioral Cancer Prevention and Control Training ProgramR25CA092408 · NCI · UNIVERSITY OF WASHINGTON · PI PATRICK, DONALD LEE · 2001 to 2015
$7.1M
PCPT and SELECT cohorts: Core Infrastructure Support for Cancer Research UM1CA182883 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TANGEN, CATHERINE M., THOMPSON, IAN M. · 2013 to 2017
$5.2M
Human and Bacterial Molecular Pathways in Cancer Risk: Modulation by DietR01CA192222 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LAMPE, JOHANNA W · 2016 to 2019
$2.9M
Vitamin D and Prostate Cancer: Biomarkers and Genetic VariationR01CA138639 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI NEUHOUSER, MARIAN L · 2010 to 2012
$1.2M
NCI NIH HHS P01 CA108964NCI NIH HHS P30 CA046934NCI NIH HHS R01 CA138639NCI NIH HHS R01 CA192222NCI NIH HHS R25 CA092408NCI NIH HHS U10 CA037429NCI NIH HHS UG1 CA189974NCI NIH HHS UM1 CA182883
6 · The paper itself

Abstract

Some, but not all, epidemiologic studies report an association between vitamin D and prostate cancer risk. The inconsistent findings might be explained in the context of modification by members of the insulin-like growth factor (IGF) axis. Data and specimens for this nested case-control study (

Indexed as

AgedBiopsyCase-Control StudiesHumansInsulin-Like Growth Factor Binding Protein 2Insulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IInsulin-Like Growth Factor IILogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProstatic NeoplasmsRisk FactorsVitamin D25-hydroxyvitamin DIGF1 protein, humanIGF2 protein, humanIGFBP3 protein, humanInsulin-Like Growth Factor Binding Protein 2Insulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IInsulin-Like Growth Factor IIVitamin Dinsulin-like growth factorlogistic regressionnested case-controlodds ratioprostate cancervitamin D

Identifiers

PMID28417914
PMCPMC5409717
OpenAlexW2606112444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.