ReviewInternational dental journal2017
Worldwide pattern of antibiotic prescription in endodontic infections.
Review in International dental journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 81 citations in OpenAlex.
- Therapeutic potential of Vaccinium species in the prevention and management of erosion and dental caries: a systematic review.Odontology · 2026Review
- Antibiotic Prescribing Practices for Apical Periodontitis and Acute Periapical Abscess in Children: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Comparative Impacts of Oral Amoxicillin, Azithromycin, and Clindamycin on Gut Microbiota and Intestinal Homeostasis.Antibiotics (Basel, Switzerland) · 2025Article
- Over-Prescription of Antibiotics for Pulpitis: A Systematic Review and Meta-Analysis of Cross-Sectional Surveys.Antibiotics (Basel, Switzerland) · 2025Review
- Antibiotic Prescribing Habits in Endodontics among Dentists in the Federation of Bosnia and Herzegovina-A Questionnaire-Based Study.Antibiotics (Basel, Switzerland) · 2024Article
- Patients' Opinions on Antibiotics in the Treatment of Dental Infections: A Cross-Sectional Survey.Journal of clinical medicine · 2024Article
- Antibiotic Over-Prescription by Dentists in the Treatment of Apical Periodontitis: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2024Review
- Systemic Antibiotic Use in Acute Irreversible Pulpitis: Evaluating Clinical Practices and Molecular Insights.International journal of molecular sciences · 2024Review
- The Outcome of Prescribing Antibiotics for the Management of Patients with Endodontic Infections.European endodontic journal · 2023Article
- Antibiotic prescribing practices for prophylaxis and therapy of oral/dental infections in pediatric patients - results of a cross-sectional study in Turkey.GMS hygiene and infection control · 2023Article
- Awareness regarding antimicrobial resistance and confidence to prescribe antibiotics in dentistry: a cross-continental student survey.Antimicrobial resistance and infection control · 2022Article
- Evaluation of antibiotic prescribing for ambulatory patients seeking primary dental care services in a public hospital in Ghana: a clinical audit study.JAC-antimicrobial resistance · 2022Article
- The Potential Application of Natural Photosensitizers Used in Antimicrobial Photodynamic Therapy against Oral Infections.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Antibiotics prescription habits of Spanish endodontists: Impact of the ESE awareness campaign and position statement.Journal of clinical and experimental dentistry · 2022Article
- Medication Prescribing Practices in Croatian Dental Offices and Their Contribution to National Consumption.International dental journal · 2021Article
- Knowledge and attitudes of Croatian Dentists Regarding Antibiotic Prescription in Endodontics: A Cross-sectional Questionnaire-based Study.Acta stomatologica Croatica · 2021Article
- Novel nanographene oxide-calcium phosphate cement inhibits Enterococcus faecalis biofilm and supports dental pulp stem cells.Journal of orthopaedic surgery and research · 2021Article
- Endodontic Infections and the Extent of Antibiotic Overprescription among Italian Dental Practitioners.Antimicrobial agents and chemotherapy · 2021Article
- Root canal microorganisms and their antibiotic susceptibility in patients with persistent endodontic infections, with and without clinical symptoms.Odontology · 2021Article
- Antibiotics Prescription by Spanish General Practitioners in Primary Dental Care.Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOdontogenic infections, and especially endodontic infections, are polymicrobial, involving a combination of Gram-positive and Gram-negative facultative anaerobes and strictly anaerobic bacteria. Therefore, antibiotics can be used as an adjunct to endodontic treatment. However, most chronic and even acute endodontic infections can be successfully managed by disinfection of the root-canal system, which eliminates the source of infection, followed by abscess drainage or tooth extraction, without the need for antibiotics. The literature provides evidence of inadequate prescribing practices by dentists. The aim of this concise review was to analyse the worldwide pattern of antibiotic prescription in endodontic infections.
methodsComprehensive searches were conducted in MEDLINE/PubMed, Wiley Online Database, Web of Science and Scopus. The databases were searched up to 13 March 2016 for studies in which dentists used systemic antibiotics to treat endodontic lesions and which reported data on the type of antibiotic prescribed and on the diagnosis of the endodontic disease treated.
resultsThe electronic and hand searches identified 69 titles, of which 25 were included in the final analysis. Amoxicillin was reported as the drug of choice for endodontic infections in most countries, and clindamycin and erythromycin were the choice for patients allergic to penicillin. Dentists worldwide prescribe antibiotics for non-indicated conditions, such as pulpitis.
conclusionAntibiotics are overprescribed for the management of endodontic infections. It is necessary to improve antibiotic-prescribing habits in the treatment of endodontic infections, as well as to introduce educational initiatives to encourage the coherent and proper use of antibiotics in such conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.