Evidence map›Paper›PMID 28417154›Full record

ArticleInternational urogynecology journal2017

Bulkamid (PAHG) in mixed urinary incontinence: What is the outcome?

Stefan Mohr, Christine Marthaler, Sara Imboden, Ash Monga, Michel D Mueller, Annette Kuhn

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The Impact of Treatment Setting on Periurethral Bulking.International urogynecology journal · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Stefan MohrDepartment of Obstetrics and Gynecology, Inselspital, Bern University Hospital, University of Bern, Effingerstr. 102, 3010, Bern, Switzerland. stefan.mohr@insel.ch.ORCID http://orcid.org/0000-0002-7218-4908
Christine MarthalerDepartment of Obstetrics and Gynecology, Inselspital, Bern University Hospital, University of Bern, Effingerstr. 102, 3010, Bern, Switzerland.
Sara ImbodenDepartment of Obstetrics and Gynecology, Inselspital, Bern University Hospital, University of Bern, Effingerstr. 102, 3010, Bern, Switzerland.
Ash MongaDepartment of Obstetrics and Gynecology, Princess Anne Hospital, Southhampton, UK.
Michel D MuellerDepartment of Obstetrics and Gynecology, Inselspital, Bern University Hospital, University of Bern, Effingerstr. 102, 3010, Bern, Switzerland.
Annette KuhnDepartment of Obstetrics and Gynecology, Inselspital, Bern University Hospital, University of Bern, Effingerstr. 102, 3010, Bern, Switzerland.
University of Bern · CHPrincess Anne Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisMixed urinary incontinence (MUI), defined as mixed symptoms of stress urinary incontinence (SUI) and overactive bladder (OAB), is a difficult entity if conservative treatment has failed. Cure rates are low compared with SUI, particularly the OAB component, may deteriorate after sling insertion. Bulking agents pose an appealing alternative for the treatment of MUI. They have shown beneficial effect in small case studies, but larger series are lacking. The aim of this prospective study was an analysis of treatment efficacy and safety profile of the bulking agent, Bulkamid, in female patients with MUI.

methodsOne hundred fifty-four women with MUI symptoms (components of SUI/OAB within the limits of 60-40% either way) received bulking therapy with polyacrylamide hydrogel (Bulkamid). Patients were followed-up 3 months postoperatively. Primary outcome was the domain Incontinence impact on the King's Health Questionnaire (KHQ). Secondary outcomes were the other KHQ domains, visual analog scale (VAS), and International Continence Society (ICS) standardized pad weight test as objective measurement of incontinence.

resultsStatistically significant improvements were found for all KHQ domains, pad weight test, and the visual analog scale (VAS) before and after bulking. Overall complication rate was 13%.

conclusionsThis study has shown improvement in MUI after bulking therapy according to both subjective and objective outcomes. We can advocate bulking therapy for treating MUI, as it is simple and safe and shows both objective and subjective improvement and relief. Long-term results (up to 1 year) are awaited.

Indexed as

Acrylic ResinsAdultAgedAged, 80 and overFemaleHumansHydrogelsMiddle AgedTreatment OutcomeUrinary IncontinenceAcrylic ResinsBulkamidHydrogelsBulking agentBulking therapyMixed urinary incontinenceOveractive bladderPeriurethral bulkingStress urinary incontinence

Identifiers

PMID28417154
OpenAlexW2606409082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.