Evidence map›Paper›PMID 28417104›Full record

ArticleJournal of audiology & otology2017

Combined Bifrontal Transcranial Direct Current Stimulation and Tailor-Made Notched Music Training in Chronic Tinnitus.

Ho Yun Lee, Myoung Su Choi, Dong Sik Chang, Chin-Saeng Cho

Registry-linked trialAbstract read
In one paragraph

Article in Journal of audiology & otology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04551404 (Transcranial Electrical and Acoustic Stimulation for Tinnitus), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04551404 nacompletednot on this mapstarted 2021, after this paper: background citation

Transcranial Electrical and Acoustic Stimulation for Tinnitus: A Randomized Double Blind Clinical Trial

TypeinterventionalSponsorUniversity of ZurichRan2021 to 2025Enrolled35ConditionsTinnitus, Tinnitus, SubjectiveArmstranscranial Random Noise Stimulation (tRNS) with acoustic stimulation (AS), transcranial Random Noise Stimulation (tRNS) without acoustic stimulation (AS)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy of tailor-made notched music training (TMNMT) in the treatment of tinnitus: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Music Therapy and Tinnitus Treatment: Systematic Review and Meta-Analysis.International archives of otorhinolaryngology · 2026
    Review
  3. Effect of Simultaneous Use of Neuromodulation and Acoustic Stimulation in the Management of Tinnitus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Clinical characteristics of subjective idiopathic tinnitus and preliminarily analyses for the effect of tinnitus multielement integration sound therapy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  8. [Improving the role of rTMS and tDCS in the treatment of chronic tinnitus by combining other rehabilitation techniques].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Review
  9. Article
  10. Tinnitus and Brain Stimulation.Current topics in behavioral neurosciences · 2021
    Article
  11. Article
  12. Article
  13. Non-Invasive Neuromodulation for Tinnitus.Journal of audiology & otology · 2020
    Review
  14. Beyond Hearing Loss: Does Tinnitus Cause Cognitive Impairment?Clinical and experimental otorhinolaryngology · 2020
    Article
  15. Review
  16. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ho Yun LeeDepartment of Otorhinolaryngology, Eulji University Medical Center, Eulji University, Daejeon, Korea.
Myoung Su ChoiDepartment of Otorhinolaryngology, Eulji University Medical Center, Eulji University, Daejeon, Korea.
Dong Sik ChangDepartment of Otorhinolaryngology, Eulji University Medical Center, Eulji University, Daejeon, Korea.
Chin-Saeng ChoDepartment of Otorhinolaryngology, Eulji University Medical Center, Eulji University, Daejeon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe evaluated the short-term treatment outcomes of combined bifrontal transcranial direct current stimulation (tDCS) and tailor-made notched music training (TMNMT) in tinnitus patients. The associations of patient characteristics with treatment responsiveness were investigated. SUBJECTS AND

methodsFour sessions of bifrontal tDCS (F4: anode, F3: cathode) and TMNMT were conducted over a 2-week period in tinnitus patients. For tDCS, the stimulation intensity was 1.5 mA and the duration was approximately 20 min. During tDCS, patients listened to music lacking the frequency band within 1 octave of the tinnitus frequency. Patients were also instructed to listen to this music at home for at least 2 hours per day. One month after the final tDCS session, loudness (LD), awareness (AW), annoyance (AN), and effect on life (EL) of tinnitus were assessed subjectively using a visual analog scale.

resultsA total of 14 patients were enrolled in this study. After treatment, a 50% or greater improvement in AN, AW, EL, and LD was observed in 57.1, 42.9, 35.7, and 28.6% of patients, respectively. Furthermore, 78.6% of patients showed a 50% or greater improvement in their tinnitus handicap inventory scores. For AN, the absence of sleep disturbance was significantly associated with treatment responsiveness (

conclusionsCombined bifrontal tDCS and TMNMT is a promising treatment for chronic tinnitus. To maximize the treatment outcomes of this therapy, sleep disturbances should also be addressed in candidate patients.

Indexed as

MusicNeuromodulationPrognosisTinnitusTreatment

Identifiers

PMID28417104
PMCPMC5392009

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.