Evidence map›Paper›PMID 28416709›Full record

ReviewJournal of bacteriology2017

Spheres of Hope, Packets of Doom: the Good and Bad of Outer Membrane Vesicles in Interspecies and Ecological Dynamics.

Jonathan B Lynch, Rosanna A Alegado

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. SypC, a symbiont outer membrane vesicle protein, impacts the development of the squid-vibrio partnership.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. The role ofJournal of oral microbiology · 2026
    Review
  3. Human gut commensalGut microbes · 2025
    Article
  4. Review
  5. Bacterial extracellular vesicles target different bacterial species, impairing cell division and diminishing their pathogenicity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Membrane vesicles can contribute to cellulose degradation bybioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. Journal of bacteriology · 2024
    Article
  12. Bacterial Membrane Vesicles for In Vitro Catalysis.Bioengineering (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Article
  15. Predatory Strategies ofMicroorganisms · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Bacterial lipopolysaccharide induces settlement and metamorphosis in a marine larva.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan B LynchPacific Biosciences Research Center, Kewalo Marine Laboratory, University of Hawai'i-Mānoa, Honolulu, Hawaii, USA jblynch@hawaii.edu ralegado@hawaii.edu.
Rosanna A AlegadoDepartment of Oceanography, Daniel K. Inouye Center for Microbial Oceanography: Research and Education, and Sea Grant College Program, University of Hawai'i-Mānoa, Honolulu, Hawaii, USA jblynch@hawaii.edu ralegado@hawaii.edu.

Funding

Determination of outer membrane vesicle composition and effector activity in the Vibrio fischeri-Euprymna scolopes symbiosisF32GM119238 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI LYNCH, JONATHAN · 2016 to 2018
$174k
NIGMS NIH HHS F32 GM119238
6 · The paper itself

Abstract

Outer membrane vesicles (OMVs) are proteoliposome nanoparticles ubiquitously produced by Gram-negative bacteria. Typically bearing a composition similar to those of the outer membrane and periplasm of the cells from which they are derived, OMVs package an array of proteins, lipids, and nucleic acids. Once considered inconsequential by-products of bacterial growth, OMVs have since been demonstrated to mediate cellular stress relief, promote horizontal gene transfer and antimicrobial activity, and elicit metazoan inflammation. Recently, OMVs have gained appreciation as critical moderators of interorganismal dynamics. In this review, we focus on recent progress toward understanding the functions of OMVs with regard to symbiosis and ecological contexts, and we propose potential avenues for future OMV studies.

Indexed as

AnimalsBacterial ProteinsGram-Negative BacteriaHost-Pathogen InteractionsLipid MetabolismNucleic AcidsSecretory VesiclesSymbiosisBacterial ProteinsNucleic Acidshost-microbe interactionsouter membrane vesicles

Identifiers

PMID28416709
PMCPMC5512217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.