Evidence map›Paper›PMID 28416706›Full record

ArticleJournal of bacteriology2017

The GAN Exonuclease or the Flap Endonuclease Fen1 and RNase HII Are Necessary for Viability of Thermococcus kodakarensis.

Brett W Burkhart, Lubomira Cubonova, Margaret R Heider, Zvi Kelman, John N Reeve, Thomas J Santangelo

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. DNA polymerase I: structure, activity, and function in bacterial DNA replication and repair.Critical reviews in biochemistry and molecular biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Archaeal DNA Replication.Annual review of microbiology · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Brett W BurkhartDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, USA.
Lubomira CubonovaDepartment of Microbiology, Ohio State University, Columbus, Ohio, USA.
Margaret R HeiderNew England Biolabs, Inc., Ipswich, Massachusetts, USA.
Zvi KelmanBiomolecular Labeling Laboratory, National Institute of Standards and Technology, Rockville, Maryland, USA.
John N ReeveDepartment of Microbiology, Ohio State University, Columbus, Ohio, USA.
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, USA thomas.santangelo@colostate.edu.
Colorado State University · USThe Ohio State University · USNational Institute of Standards and Technology · USNew England Biolabs (United States) · US

Funding

Mechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5M
A Model Archaeal System: Genetic Tools and Resources for T. kodakarensisR24GM098176 · NIGMS · OHIO STATE UNIVERSITY · PI REEVE, JOHN NEWTON · 2011 to 2014
$1.2M
NIGMS NIH HHS R01 GM100329NIGMS NIH HHS R24 GM098176
6 · The paper itself

Abstract

Many aspects of and factors required for DNA replication are conserved across all three domains of life, but there are some significant differences surrounding lagging-strand synthesis. In

Indexed as

ExoribonucleasesFlap EndonucleasesGene DeletionGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicGenome, BacterialMicrobial ViabilityThermococcusexoribonuclease HExoribonucleasesFlap EndonucleasesArchaeaCMG complexDNA replicationflap endonuclease Fen1GINS-associated nuclease GANOkazaki fragmentRNase HII

Identifiers

PMID28416706
PMCPMC5472818
OpenAlexW2606270492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.