ArticleProceedings of the National Academy of Sciences of the United States of America2017
Sensorimotor-independent development of hands and tools selectivity in the visual cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 85 citations in OpenAlex.
- Investigating action topography in visual cortex and deep artificial neural networks.Nature communications · 2025Article
- Action-type mapping principles extend beyond evolutionarily conserved actions, even in people born without hands.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Intrinsic Functional Connectivity Patterns of The Object-Selective Visual Areas.Noro psikiyatri arsivi · 2025Article
- A 7T fMRI investigation of hand and tool areas in the lateral and ventral occipitotemporal cortex.PloS one · 2024Article
- Novel objects with causal event schemas elicit selective responses in tool- and hand-selective lateral occipitotemporal cortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The parietal lobe evolution and the emergence of material culture in the human genus.Brain structure & function · 2023Review
- Are reaching and grasping effector-independent? Similarities and differences in reaching and grasping kinematics between the hand and foot.Experimental brain research · 2022Article
- Development of white matter tracts between and within the dorsal and ventral streams.Brain structure & function · 2022Article
- Hand-Selective Visual Regions Represent How to Grasp 3D Tools: Brain Decoding during Real Actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Towards Strong Inference in Research on Embodiment - Possibilities and Limitations of Causal Paradigms.Journal of cognition · 2021Article
- Motor Imagery Training of Reaching-to-Grasp Movement Supplemented by a Virtual Environment in an Individual With Congenital Bilateral Transverse Upper-Limb Deficiency.Frontiers in psychology · 2021Article
- Consensus Paper: Cerebellum and Social Cognition.Cerebellum (London, England) · 2020Review
- Evidence for an effector-independent action system from people born without hands.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- What Does Dorsal Cortex Contribute to Perception?Open mind : discoveries in cognitive science · 2020Article
- Is an artificial limb embodied as a hand? Brain decoding in prosthetic limb users.PLoS biology · 2020Article
- Motor control drives visual bodily judgements.Cognition · 2020Article
- The Neural Representations of Movement across Semantic Categories.Journal of cognitive neuroscience · 2019Article
- Brain Activation During Conceptual Processing of Action and Sound Verbs.Advances in cognitive psychology · 2019Article
- Plasticity based on compensatory effector use in the association but not primary sensorimotor cortex of people born without hands.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Artificial limb representation in amputees.Brain : a journal of neurology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The visual occipito-temporal cortex is composed of several distinct regions specialized in the identification of different object kinds such as tools and bodies. Its organization appears to reflect not only the visual characteristics of the inputs but also the behavior that can be achieved with them. For example, there are spatially overlapping responses for viewing hands and tools, which is likely due to their common role in object-directed actions. How dependent is occipito-temporal cortex organization on object manipulation and motor experience? To investigate this question, we studied five individuals born without hands (individuals with upper limb dysplasia), who use tools with their feet. Using fMRI, we found the typical selective hand-tool overlap (HTO) not only in typically developed control participants but also in four of the five dysplasics. Functional connectivity of the HTO in the dysplasics also showed a largely similar pattern as in the controls. The preservation of functional organization in the dysplasics suggests that occipito-temporal cortex specialization is driven largely by inherited connectivity constraints that do not require sensorimotor experience. These findings complement discoveries of intact functional organization of the occipito-temporal cortex in people born blind, supporting an organization largely independent of any one specific sensory or motor experience.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.