Evidence map›Paper›PMID 28416610›Full record

ArticleThe Journal of biological chemistry2017

Evidence for shear-mediated Ca

Zeki Ilkan, Joy R Wright, Alison H Goodall, Jonathan M Gibbins, Chris I Jones, Martyn P Mahaut-Smith

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 98 citations in OpenAlex.

  1. Mechanisms of Piezo1-Mediated Mechanotransduction in Thrombotic Diseases.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation.Journal of cellular and molecular medicine · 2024
    Article
  11. Mechanism of Bile Acid in Regulating Platelet Function and Thrombotic Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. The shear rate promotes pinocytosis of extracellular dextran in platelets.Clinical hemorheology and microcirculation · 2024
    Article
  19. The platelet storage lesion, what are we working for?Journal of clinical laboratory analysis · 2024
    Review
  20. Why platelet mechanotransduction matters for hemostasis and thrombosis.Journal of thrombosis and haemostasis : JTH · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zeki IlkanFrom the Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 7RH, United Kingdom.
Joy R WrightFrom the Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 7RH, United Kingdom.
Alison H Goodallthe Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, United Kingdom, and.
Jonathan M Gibbinsthe School of Biological Sciences, University of Reading, Reading RG6 6AS, United Kingdom.
Chris I Jonesthe School of Biological Sciences, University of Reading, Reading RG6 6AS, United Kingdom.
Martyn P Mahaut-SmithFrom the Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 7RH, United Kingdom, mpms1@le.ac.uk.
National Institute for Health Research · GBUniversity of Leicester · GBUniversity of Reading · GB

Funding

British Heart Foundation PG/11/56British Heart Foundation PG/11/56/29001British Heart Foundation RG/09/011/28094British Heart Foundation RG/15/2/31224Medical Research Council
6 · The paper itself

Abstract

The role of mechanosensitive (MS) Ca

Indexed as

Calcium SignalingBlood PlateletsCalciumCell LineFemaleHumansIntercellular Signaling Peptides and ProteinsIon ChannelsMaleMegakaryocytesPeptidesReceptors, Purinergic P2X1Spider VenomsStress, MechanicalThrombosisCalciumIntercellular Signaling Peptides and ProteinsIon ChannelsMTx4 protein, Grammostola spatulataPeptidesPIEZO1 protein, humanReceptors, Purinergic P2X1Spider Venomscalciumion channelmechanotransductionPiezo1plateletshear stress

Identifiers

PMID28416610
PMCPMC5454102
OpenAlexW2605543068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.