Evidence map›Paper›PMID 28416555›Full record

ArticleAntimicrobial agents and chemotherapy2017

Mycobacterium tuberculosis Proteome Response to Antituberculosis Compounds Reveals Metabolic "Escape" Pathways That Prolong Bacterial Survival.

Lia Danelishvili, Natalia Shulzhenko, Jessica J J Chinison, Lmar Babrak, Jialu Hu, Andriy Morgun, Gregory Burrows, Luiz E Bermudez

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Sequence of Antibiotic Administration for the Treatment ofAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Using Omics to Study Leprosy, Tuberculosis, and Other Mycobacterial Diseases.Frontiers in cellular and infection microbiology · 2022
    Review
  11. Microorganisms · 2021
    Article
  12. Review
  13. Article
  14. The unfoldase ClpC1 ofThe Journal of biological chemistry · 2020
    Article
  15. Exposure ofMicroorganisms · 2020
    Article
  16. Metabolic Changes ofPathogens (Basel, Switzerland) · 2020
    Article
  17. Quantitative analysis ofClinical proteomics · 2019
    Article
  18. Rewiring of Metabolic Network inFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lia DanelishviliDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA lia.danelishvili@oregonstate.edu luiz.bermudez@oregonstate.edu.
Natalia ShulzhenkoDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.
Jessica J J ChinisonDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.
Lmar BabrakDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA.
Jialu HuDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, USA.
Andriy MorgunDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon, USA.
Gregory BurrowsDepartment of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, USA.
Luiz E BermudezDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA lia.danelishvili@oregonstate.edu luiz.bermudez@oregonstate.edu.
Oregon State University · USOregon Health & Science University · US

Funding

Gut microbiota mediates the interplay between immunity and glucose metabolismR01DK103761 · NIDDK · OREGON STATE UNIVERSITY · PI SHULZHENKO, NATALIA · 2015 to 2019
$1.7M
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusR00NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2021 to 2023
$729k
Strategy for anti-tuberculosis therapyR21AI110078 · NIAID · OREGON STATE UNIVERSITY · PI BERMUDEZ, LUIZ EDUARDO · 2014 to 2015
$402k
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusK99NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2020 to 2020
$93k
NIAID NIH HHS R21 AI110078NIDDK NIH HHS R01 DK103761NINR NIH HHS K99 NR018886NINR NIH HHS R00 NR018886
6 · The paper itself

Abstract

Tuberculosis (TB) continues to be one of the most common bacterial infectious diseases and is the leading cause of death in many parts of the world. A major limitation of TB therapy is slow killing of the infecting organism, increasing the risk for the development of a tolerance phenotype and drug resistance. Studies indicate that

Indexed as

Antitubercular AgentsDiarylquinolinesFluoroquinolonesIsoniazidMefloquineMoxifloxacinMycobacterium tuberculosisProteomeProteomicsRifampinAntitubercular AgentsbedaquilineDiarylquinolinesFluoroquinolonesIsoniazidMefloquineMoxifloxacinProteomeRifampinbedaquilinedrug targetsINHM. tuberculosisMXFproteomicsRIFRMPsynergistic targetsTMC207

Identifiers

PMID28416555
PMCPMC5487666
OpenAlexW2606782815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.