ReviewNeuropsychologia2017
Executive functioning and substance use in adolescence: Neurobiological and behavioral perspectives.
Review in Neuropsychologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating the validity of game-based assessments measuring cognitive function among children and adolescents: A systematic review and meta-analysis.Progress in brain research · 2023Pooled it
- Are School-Aged Children Who Self-Identify as Neurodivergent at Greater Risk of Substance Misuse? A Study of 20 000 Secondary School Students.Child: care, health and development · 2026Article
- rTMS Suppresses Tobacco Craving via Enhanced Prefronto-Striato-Thalamic Connectivity.Addiction biology · 2026Article
- The relationship between regular substance use and cost comparisons in stable and volatile learning contexts.Translational psychiatry · 2026Article
- Fueling the Cycle: Attachment, Cognition, and Emotion in Substance-Using Incarcerated Young Adults.Clinical neuropsychiatry · 2025Article
- Neural Signatures of Cognitive Control Predict Future Adolescent Substance Use Onset and Frequency.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- The role of executive functioning in smoking cessation: A scoping review.Drug and alcohol review · 2025Article
- Emotional trade-offs of neural sensitivity to social threat and reward in adolescent girls.Social cognitive and affective neuroscience · 2025Article
- Investigating resting-state functional connectivity changes within procedural memory network across neuropsychiatric disorders using fMRI.BMC medical imaging · 2025Article
- Cognitive Dysfunction in the Addictions (CDiA): protocol for a neuron-to-neighbourhood collaborative research program.Frontiers in psychiatry · 2025Article
- The Limbic System in Co-Occurring Substance Use and Anxiety Disorders: A Narrative Review Using the RDoC Framework.Brain sciences · 2024Review
- Childhood executive control and adolescent substance use: Mediation via parent-child relationship quality.Family relations · 2024Article
- Negative Affect, Sensation Seeking, and Adolescent Substance Use Development: The Moderating Role of Executive Function.Journal of youth and adolescence · 2024Article
- Identifying Game-Based Digital Biomarkers of Cognitive Risk for Adolescent Substance Misuse: Protocol for a Proof-of-Concept Study.JMIR research protocols · 2023Article
- An exploratory follow-up study of cannabis use and decision-making under various risk conditions within adolescence.Neuropsychology · 2023Article
- The mediating role of self-regulation on the link between child maltreatment and later substance use among Latinx youth.Child abuse & neglect · 2023Article
- Childhood executive control and adolescent substance use initiation: the mediating roles of physical and relational aggression and prosocial behavior.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2023Article
- Is there a causal relationship between executive function and liability to mental health and substance use? A Mendelian randomization approach.Royal Society open science · 2022Article
- Neural cognitive control moderates the longitudinal link between hedonia and substance use across adolescence.Developmental cognitive neuroscience · 2022Article
- Development of a neuropsychological assessment in smoking.Revista de neurologia · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The current review is guided by the theoretical perspective that emphasizes the regulating role of executive functioning (Carver et al., 2009) and presents studies that elucidate the ways that executive functioning (inhibition and working memory) explain individual differences in adolescent substance use independently or by regulating the reactive system (reward and punishment sensitivity). Behavioral studies indicate that main effects of executive functioning on adolescent substance use are often nonsignificant or weak in effect sizes. In contrast, emerging evidence suggests consistent and stronger regulating effects of executive functioning over reward and punishment sensitivity. Functional neuroimaging studies reveal significant associations between executive functioning task-related hemodynamic responses and substance use with strong effect sizes. There is also direct evidence from studies testing statistical interactions of the regulating effects of EF-related brain activation, and indirect evidence in studies examining functional connectivity, temporal discounting, and reinforced control. We note key future directions and ways to address limitations in existing work.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.