Evidence map›Paper›PMID 28415983›Full record

ArticleBMC public health2017

Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution.

Herve Lawin, Lucie Ayi Fanou, Vikkey Hinson, Jacqueline Wanjiku, N Kingsley Ukwaja, Stephen B Gordon, Benjamin Fayomi, John R Balmes, Parfait Houngbegnon, Euripide Avokpaho and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Herve LawinUnit of Teaching and Research in Occupational and Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin. hervelawin@yahoo.fr.
Lucie Ayi FanouLaboratoire de Biochimie et de Biologie Moléculaire, FAST/UAC, Cotonou, Benin.
Vikkey HinsonUnit of Teaching and Research in Occupational and Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
Jacqueline WanjikuDepartment of Internal Medicine, Egerton University, Njoro, Kenya.
N Kingsley UkwajaDepartment of Internal Medicine, Federal Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
Stephen B GordonLiverpool School of Tropical Medicine, Liverpool, UK.
Benjamin FayomiUnit of Teaching and Research in Occupational and Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
John R BalmesDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, USA.
Parfait HoungbegnonInstitut Regional de Santé Publique, University of Abomey Calavi, Cotonou, Benin.
Euripide AvokpahoUnit of Teaching and Research in Occupational and Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
Ambaliou SanniLaboratoire de Biochimie et de Biologie Moléculaire, FAST/UAC, Cotonou, Benin.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn urban settings of Africa with rapidly increasing population, traffic-related air pollution is a major contributor to outdoor air pollution (OAP). Although OAP has been identified as a leading cause of global morbidity and mortality, there is however, lack of a simple biomarker to assess levels of exposure to OAP in resource-poor settings. This study evaluated the role of exhaled carbon monoxide (exhCO) as a potential biomarker of exposure to ambient carbon monoxide (ambCO) from OAP.

methodsThis was a descriptive study conducted among male commercial motorcycle riders in Cotonou - the economic capital of Benin. The participants' AmbCO was measured using a portable carbon monoxide (CO) data logger for 8 h during the period of their shift. ExhCO was measured just before and immediately after their shift (8-h) Participants were asked not to cook or to smoke during the day of the measurements. Linear regression analysis was used to assess the association between ambCO and exhCO for the last 2, 4 and 6 h of their shift.

resultsOf 170 participants who completed the study, their mean ± SD age was 42.2 ± 8.4 years, and their mean ± SD daily income was 7.3 ± 2.7$. Also, 95% of the participants' used solid fuels for cooking and only 2% had ever smoked. Average exhCO increased by 5.1 ppm at the end of the shift (p = 0.004). Post-shift exhCO was significantly associated to ambCO, this association was strongest for the last 2 h of OAP exposure before exhCO measurement (β = 0.34, p < 0.001).

conclusionExhCO level was associated with recent exposure to ambCO from OAP with measurable increase after 8 h of exposure. These findings suggest that ExhCO may be a potential biomarker of short-term exposure to OAP.

Indexed as

ExhalationMotorcyclesAdultAir PollutionBeninBiomarkersCarbon MonoxideCross-Sectional StudiesHumansLinear ModelsMaleMiddle AgedOccupational ExposureUrban PopulationBiomarkersCarbon MonoxideAir pollutionBiomarkerCarbon monoxide

Identifiers

PMID28415983
PMCPMC5392985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.