ArticleThe Journal of international medical research2017
Effective treatment of ketamine-associated cystitis with botulinum toxin type a injection combined with bladder hydrodistention.
Article in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 28 citations in OpenAlex.
- Ketamine uropathy: an update on pathophysiology, complications, and treatment options.The Canadian journal of urology · 2026Review
- Clinical Approach to Recurrent Voiding Dysfunction, Dysuria, and Pelvic Pain Persisting for at Least 3 Months.International neurourology journal · 2022Article
- Molecular Pathophysiology and Potential Therapeutic Strategies of Ketamine-Related Cystitis.Biology · 2022Review
- Ketamine-Induced Cystitis: A Comprehensive Review of the Urologic Effects of This Psychoactive Drug.Health psychology research · 2022Article
- Comparison of bladder autoaugmentation by transurethral vesicomyotomy and hydrodistention for ketamine cystitis.Translational andrology and urology · 2021Article
- Urethroscrotal fistula complicating large spermatocele in a male ketamine abuser: A case report.Urology case reports · 2020Article
- Efficacy of cystectasia in the treatment of ketamine-induced bladder contracture.Translational andrology and urology · 2020Article
- A survey for ketamine abuse and its relation to the lower urinary tract symptoms in Taiwan.Scientific reports · 2019Article
- Article
- Pathophysiology, clinical presentation, and management of ketamine-induced cystitis.Tzu chi medical journalArticle
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective Ketamine-associated cystitis (KAC) has been described in a few case reports, but its treatment in a relatively large number of patients has not been documented. This study aimed to describe our experience of treatment of 36 patients with KAC. Methods Thirty-six patients (30 males and 6 females, aged 19-38 years) with KAC, who had previously taken a muscarinic receptor blocker and/or antibiotics, but without symptomatic relief, were treated with botulinum toxin A injection combined with bladder hydrodistention. Urodynamic testing, and the O'Leary-Sant interstitial cystitis symptom index (ICSI) and problem index (ICPI) were used to evaluate baseline values and improvement before and after the treatment. Results One month post-treatment, all patients achieved marked relief of symptoms. The nocturia time was markedly reduced, while bladder capacity, the interval between micturition, the void volume, and the maximum flow rate were remarkably increased at 1 month. Additionally, the ICSI and ICPI were significantly improved. Conclusion Botulinum toxin A injection along with bladder hydrodistention is effective for managing KAC.
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