Evidence map›Paper›PMID 28415946›Full record

ArticleThe Journal of international medical research2017

Azacitidine-induced acute lung injury in a patient with therapy-related myelodysplastic syndrome.

Shinichi Makita, Wataru Munakata, Daisuke Watabe, Akiko Miyagi Maeshima, Hirokazu Taniguchi, Kosuke Toyoda, Nobuhiko Yamauchi, Suguru Fukuhara, Dai Maruyama, Yukio Kobayashi and 1 more

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In one paragraph

Article in The Journal of international medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Shinichi Makita1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Wataru Munakata1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Daisuke Watabe2 Departments of Pharmacy, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Akiko Miyagi Maeshima3 Departments of Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Hirokazu Taniguchi3 Departments of Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Kosuke Toyoda1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Nobuhiko Yamauchi1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Suguru Fukuhara1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Dai Maruyama1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Yukio Kobayashi1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Kensei Tobinai1 Departments of Hematology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
National Cancer Center Hospital East · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azacitidine is a first-in-class demethylating agent, and it is widely used globally as a first-line treatment for higher-risk myelodysplastic syndrome (MDS). Here, we report the case of a patient with MDS who suffered from a rare adverse event, an acute lung injury (ALI), which was suspected to have been caused by azacitidine and was successfully treated with corticosteroids. As it is a rare, but critical, adverse event, clinicians should consider ALI as one of the differential diagnoses in cases where 1) pneumonia and fever of unknown etiology arise in MDS patients treated with azacitidine, 2) antimicrobial agents are not effective, and 3) microbiological tests produce negative results.

Indexed as

Acute Lung InjuryAdrenal Cortex HormonesAgedAntimetabolites, AntineoplasticAzacitidineHumansLymphoma, FollicularMaleMyelodysplastic SyndromesPrednisoloneTomography, X-Ray ComputedAdrenal Cortex HormonesAntimetabolites, AntineoplasticAzacitidinePrednisoloneacute lung injuryAzacitidinefollicular lymphomamyelodysplastic syndrome

Identifiers

PMID28415946
PMCPMC5536648
OpenAlexW2596593358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.