Evidence map›Paper›PMID 28415644›Full record

ReviewOncotarget2017

Long non-coding RNAs in cutaneous melanoma: clinical perspectives.

Eva Hulstaert, Lieve Brochez, Pieter-Jan Volders, Jo Vandesompele, Pieter Mestdagh

Open access · diamondAbstract readReview
In one paragraph

Review in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

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  11. Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.Proceedings of the National Academy of Sciences of the United States of America · 2019
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  20. cfRNAs as biomarkers in oncology - still experimental or applied tool for personalized medicine already?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eva HulstaertDepartment of Dermatology, Ghent University Hospital, Ghent, Belgium.
Lieve BrochezDepartment of Dermatology, Ghent University Hospital, Ghent, Belgium.
Pieter-Jan VoldersCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Jo VandesompeleCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Pieter MestdaghCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding potential. There is growing evidence that lncRNAs play an important role in gene regulation, including oncogenesis. We present 13 lncRNA genes involved in the pathogenesis of cutaneous melanoma through a variety of pathways and molecular interactions. Some of these lncRNAs are possible biomarkers or therapeutic targets for malignant melanoma.

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticAnimalsCutaneous Malignant MelanomaEpistasis, GeneticHumansMelanomaMutationPrognosisRNA, Long NoncodingSkin NeoplasmsBiomarkers, TumorRNA, Long Noncodingbiomarkerscancer therapylong non-coding RNAmelanoma

Identifiers

PMID28415644
PMCPMC5522162
OpenAlexW2603473536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.