Evidence map›Paper›PMID 28415159›Full record

ArticleJournal of pathology and translational medicine2017

Comparison of Unsatisfactory Samples from Conventional Smear versus Liquid-Based Cytology in Uterine Cervical Cancer Screening Test.

Hoiseon Jeong, Sung Ran Hong, Seoung-Wan Chae, So-Young Jin, Hye Kyoung Yoon, Juhie Lee, Eun Kyung Kim, Sook Tai Ha, Sung Nam Kim, Eun-Jung Park and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of pathology and translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. The Role of p16/Ki67 Dual Staining in Cervical Cancer Screening.Current issues in molecular biology · 2023
    Review
  7. Article
  8. Article
  9. Current Status of and Perspectives on Cervical Cancer Screening in Korea.Journal of pathology and translational medicine · 2019
    Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Hoiseon JeongDepartment of Pathology, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea.
Sung Ran HongDepartment of Pathology, Cheil General Hospital and Women's Health Care Center, Dankook University College of Medicine, Seoul, Korea.
Seoung-Wan ChaeDepartment of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
So-Young JinDepartment of Pathology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
Hye Kyoung YoonDepartment of Pathology, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Juhie LeeDepartment of Pathology, Kyung Hee University School of Medicine, Seoul, Korea.
Eun Kyung KimDepartment of Pathology, Eulji General Hospital, Seoul, Korea.
Sook Tai HaT&C Diagnostic Pathology Clinic, Seoul, Korea.
Sung Nam KimSamkwang Medical Laboratories, Seoul, Korea.
Eun-Jung ParkForyou Pathology Laboratories, Gwangju, Korea.
Jong Jae JungForyou Pathology Laboratories, Gwangju, Korea.
Sun Hee SungDepartment of Pathology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
Sung-Chul LimDepartment of Pathology, Chosun University School of Medicine, Gwangju, Korea.
Chosun University · KRDankook University · KRDr Youth Clinic · KREulji Medical Center · KREwha Womans University · KRInje University Busan Paik Hospital · KRKorea University Medical Center · KRKyung Hee University · KRSoonchunhyang University Hospital Seoul · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cytology for uterine cervical cancer screening has transitioned from conventional smear (CS) to liquid-based cytology (LBC), which has many advantages. The aim of this study was to compare the proportion of unsatisfactory specimens from CS versus LBC at multiple institutions including general hospitals and commercial laboratories.

methodsEach participating institution provided a minimum of 500 Papanicolaou (Pap) test results for analysis. Pap tests were classified according to the participating institution (commercial laboratory or general hospital) and the processing method (CS, ThinPrep, SurePath, or CellPrep). The causes of unsatisfactory results were classified as technical problems, scant cellularity, or complete obscuring factors.

resultsA total of 38,956 Pap test results from eight general hospitals and three commercial laboratories were analyzed. The mean unsatisfactory rate of LBC was significantly lower than that of CS (1.26% and 3.31%, p = .018). In the LBC method, samples from general hospitals had lower unsatisfactory rates than those from commercial laboratories (0.65% vs 2.89%, p = .006). The reasons for unsatisfactory results were heterogeneous in CS. On the other hand, 66.2% of unsatisfactory results in LBC were due to the scant cellularity.

conclusionsUnsatisfactory rate of cervical cancer screening test results varies according to the institution and the processing method. LBC has a significantly lower unsatisfactory rate than CS.

Indexed as

Cervical cytologyConventional smearLiquid-based cytologyPapanicolaou testUnsatisfactory

Identifiers

PMID28415159
PMCPMC5445207
OpenAlexW2606766377

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.