Evidence map›Paper›PMID 28414272›Full record

ArticleeLife2017

Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons.

Catherine M Drerup, Amy L Herbert, Kelly R Monk, Alex V Nechiporuk

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Metabolic trajectories in developing human neocortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Self-renewal of neuronal mitochondria through asymmetric division.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. World journal of oncology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. ALS-Linked VapB P56S Mutation Alters Neuronal Mitochondrial Turnover at the Synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  17. Review
  18. VezA/vezatin facilitates proper assembly of the dynactin complex in vivo.bioRxiv : the preprint server for biology · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Catherine M DrerupDepartment of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, United States.ORCID http://orcid.org/0000-0002-0219-3075
Amy L HerbertDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, United States.
Kelly R MonkDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, United States.
Alex V NechiporukDepartment of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, United States.ORCID http://orcid.org/0000-0002-8295-8188
Washington University in St. Louis · USNational Institutes of Health · USOregon Health & Science University · US

Funding

TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Regulation of retrograde cargo transport in axonsZIAHD008964 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DRERUP, CATHERINE M · 2017 to 2020
$2.8M
Chemical and genetic screens for modulators of nervous system development and myelinationR01HD080601 · NICHD · WASHINGTON UNIVERSITY · PI MONK, KELLY R · 2014 to 2018
$1.6M
Genetic analyses of axon transport and microtubule dynamics in ZebrafishR01HD072844 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI NECHIPORUK, ALEX · 2012 to 2016
$1.6M
Identifying modulators of dynein-based cargo motilityK99NS086903 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI DRERUP, CATHERINE M · 2014 to 2015
$181k
Control of myelinating glial cell development by actr10F31NS096814 · NINDS · WASHINGTON UNIVERSITY · PI HERBERT, AMY · 2016 to 2017
$61k
NICHD NIH HHS R01 HD072844NICHD NIH HHS R01 HD080601NIGMS NIH HHS T32 GM007067NINDS NIH HHS F31 NS096814NINDS NIH HHS K99 NS086903
6 · The paper itself

Abstract

Mitochondrial transport in axons is critical for neural circuit health and function. While several proteins have been found that modulate bidirectional mitochondrial motility, factors that regulate

Indexed as

AnimalsAxonsBiological TransportDynactin ComplexGenetic TestingMitochondriaMutationProtein BindingZebrafishZebrafish ProteinsDynactin ComplexZebrafish Proteinsactr10axonal transportdevelopmental biologydynactindyneinmitochondrianeurosciencep150stem cellszebrafish

Identifiers

PMID28414272
PMCPMC5413347
OpenAlexW2607337636

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.