Evidence map›Paper›PMID 28413824›Full record

ArticleeNeuro

Perturbation of Serotonin Homeostasis during Adulthood Affects Serotonergic Neuronal Circuitry.

Marta Pratelli, Sara Migliarini, Barbara Pelosi, Francesco Napolitano, Alessandro Usiello, Massimo Pasqualetti

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Impact of Serotonin Deficiency on Circadian Dopaminergic Rhythms.International journal of molecular sciences · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Serotonergic Axons as 3D-Walks.ACS chemical neuroscience · 2019
    Article
  19. Serotonin induces or inhibits neuritic regeneration of leech CNS neurons depending on neuronal identity.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marta PratelliDepartment of Biology Unit of Cell and Developmental Biology, University of Pisa, Pisa 56127, Italy.ORCID 0000-0002-2989-4824
Sara MigliariniDepartment of Biology Unit of Cell and Developmental Biology, University of Pisa, Pisa 56127, Italy.ORCID 0000-0003-2741-269X
Barbara PelosiDepartment of Biology Unit of Cell and Developmental Biology, University of Pisa, Pisa 56127, Italy.ORCID 0000-0002-2829-2979
Francesco NapolitanoCeinge Biotecnologie Avanzate, Naples 80145, Italy.ORCID 0000-0003-0884-1851
Alessandro UsielloCeinge Biotecnologie Avanzate, Naples 80145, Italy.ORCID 0000-0001-9203-853X
Massimo PasqualettiDepartment of Biology Unit of Cell and Developmental Biology, University of Pisa, Pisa 56127, Italy.ORCID 0000-0002-0844-8139
University of Pisa · ITCeinge Biotecnologie Avanzate (Italy) · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence shows that the neurotransmitter serotonin (5-HT) modulates the fine-tuning of neuron development and the establishment of wiring patterns in the brain. However, whether serotonin is involved in the maintenance of neuronal circuitry in the adult brain remains elusive. Here, we use a

Indexed as

5-HydroxytryptophanAnimalsBrain-Derived Neurotrophic FactorGene Expression RegulationGreen Fluorescent ProteinsHomeostasisMiceMice, Inbred C57BLMice, TransgenicMidline Thalamic NucleiNerve NetNeural PathwaysRNA, MessengerSerotonergic NeuronsSerotoninSerotonin Agents5-HydroxytryptophanBrain-Derived Neurotrophic FactorGreen Fluorescent ProteinsRNA, MessengerSerotoninSerotonin AgentsSerotonin Plasma Membrane Transport ProteinsTph2 protein, mouseTryptophan Hydroxylase5-hydroxytryptophanserotonergic innervationsserotoninserotonin homeostasistryptophan hydroxylase 2

Identifiers

PMID28413824
PMCPMC5388670
OpenAlexW2605099216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.