Evidence map›Paper›PMID 28413770›Full record

ArticleCurrent opinion in chemical engineering2017

Biophysical regulation of cell reprogramming.

Sze Yue Wong, Jennifer Soto, Song Li

Abstract read
In one paragraph

Article in Current opinion in chemical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Organ-on-a-Chip for Cancer and Immune Organs Modeling.Advanced healthcare materials · 2019
    Review
  15. Engineering Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sze Yue WongDepartment of Bioengineering, University of California, Berkeley.
Jennifer SotoDepartment of Bioengineering, University of California, Berkeley.
Song LiDepartment of Bioengineering, University of California, Berkeley.

Funding

Multipotent stem cells for tissue regenerationR01EB012240 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI LI, SONG · 2010 to 2013
$1.9M
In Situ Regeneration of Blood VesselR01HL121450 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, SONG · 2015 to 2018
$1.8M
Stem Cells in Vascular RemodelingR01HL117213 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, SONG · 2013 to 2016
$1.4M
NHLBI NIH HHS R01 HL117213NHLBI NIH HHS R01 HL121450NIBIB NIH HHS R01 EB012240
6 · The paper itself

Abstract

Induced pluripotent stem (iPS) cell reprogramming and direct reprogramming are promising approaches for disease modeling and personalized medicine. However, these processes are yet to be optimized. Biomaterials are increasingly integrated into cell reprogramming strategies in order to engineer the microenvironment, improve reprogramming efficiency and achieve effective in situ cell reprogramming. Although there are some studies on the role of biomaterials in iPS cell reprogramming, their effect on direct cell conversion has not been fully explored. Here we review the recent advances in the use of biomaterials for iPS cell reprogramming and direct reprogramming, with a focus on the biophysical aspect. We further highlight the future challenges and directions of the field.

Identifiers

PMID28413770
PMCPMC5390558

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.