Evidence map›Paper›PMID 28413748›Full record

ReviewChemistryOpen2017

Thiamine Assays-Advances, Challenges, and Caveats.

Katie A Edwards, Nicole Tu-Maung, Krystal Cheng, Binbin Wang, Antje J Baeumner, Clifford E Kraft

Open access · goldAbstract readReview
In one paragraph

Review in ChemistryOpen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Article
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  11. Review
  12. Article
  13. Article
  14. Review
  15. Promising Bioactivity of Vitamin BAntioxidants (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Katie A EdwardsDepartment of Natural Resources Cornell University Ithaca NY 14853 USA.ORCID 0000-0002-8826-7863
Nicole Tu-MaungDepartment of Natural Resources Cornell University Ithaca NY 14853 USA.
Krystal ChengDepartment of Natural Resources Cornell University Ithaca NY 14853 USA.
Binbin WangDepartment of Natural Resources Cornell University Ithaca NY 14853 USA.
Antje J BaeumnerInstitute for Analytical Chemistry, Chemo and Biosensors University of Regensburg Regensburg 93040 Germany.
Clifford E KraftDepartment of Natural Resources Cornell University Ithaca NY 14853 USA.
Cornell University · USUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiamine (vitamin B1) is essential to the health of all living organisms and deficiency has long been associated with diseases in animals such as fish, birds, alligators, and domesticated ruminant mammals. Thiamine is also implicated in several human diseases including Alzheimer's, diabetes, dementia, depression and, most notably, Wernicke-Korsakoff syndrome and Beriberi disease. Yet, highly sensitive and specific detection of thiamine remains an analytical challenge, as pM to nm levels of thiamine need to be detected in environmental and human samples, respectively, various phosphorylated variants need to be discriminated, and rapid on-site detection would be highly desirable. Furthermore, appropriate sample preparation is mandatory, owing to the complexity of the relevant sample matrices including fish tissues, ocean water, and body fluids. This Review has two objectives. First, it provides a thorough overview of analytical techniques published for thiamine detection over the last 15 years. Second, it describes the principles of analytical approaches that are based on biorecognition and may open up new avenues for rapid and high-throughput thiamine analysis. Most notably, periplasmic binding proteins, ribozymes, and aptamers are of particular interest, as they function as bioaffinity recognition elements that can fill an important assay technology gap, owing to the unavailability of thiamine-specific commercial antibodies. Finally, the authors provide brief evaluations of key outcomes of the major assay concepts and suggest how innovative techniques could help develop sensitive and specific thiamine analytical test systems.

Indexed as

biosensingfluorescence spectroscopyliquid chromatographysample preparationthiamine deficiency

Identifiers

PMID28413748
PMCPMC5390807
OpenAlexW2594346557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.