Evidence map›Paper›PMID 28413715›Full record

ArticleBrain and behavior2017

Brain serotonin 4 receptor binding is inversely associated with verbal memory recall.

Dea S Stenbæk, Patrick M Fisher, Brice Ozenne, Emil Andersen, Liv V Hjordt, Brenda McMahon, Steen G Hasselbalch, Vibe G Frokjaer, Gitte M Knudsen

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Chronic, combinatorial targeting of NMDARs and 5-HTNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dea S StenbækNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.ORCID 0000-0002-5439-4637
Patrick M FisherNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Brice OzenneNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Emil AndersenNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Liv V HjordtNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Brenda McMahonNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Steen G HasselbalchNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Vibe G FrokjaerNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Gitte M KnudsenNeurobiology Research Unit and Center for Integrated Molecular Brain Imaging The Neuroscience Centre Rigshospitalet Copenhagen Denmark.
Copenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe have previously identified an inverse relationship between cerebral serotonin 4 receptor (5-HT

methodsTwenty-four healthy volunteers were scanned with the 5-HT

resultsWe observed a significant inverse association across all regions between 5-HT

conclusionOur findings replicate our previous observation of a negative association between 5-HT

Indexed as

AdultBrainEmotionsFemaleHumansMaleMental RecallMiddle AgedNeuropsychological TestsPiperidinesPositron-Emission TomographyRadiopharmaceuticalsReceptors, Serotonin, 5-HT4Speech PerceptionYoung AdultPiperidinesRadiopharmaceuticalsReceptors, Serotonin, 5-HT4SB 2071455‐HT4 receptoraffective wordslatent variable modelnegative biasespositron emission tomography

Identifiers

PMID28413715
PMCPMC5390847
OpenAlexW2596483084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.