Evidence map›Paper›PMID 28413656›Full record

ArticleMolecular and clinical oncology2017

Effect of Ki-67 assessment in the distribution of breast cancer subtypes: Evaluation in a cohort of Latin American patients.

Alejandro Yábar, Rosa Meléndez, Silvia Muñoz, Hugo Deneo, Jimena Freire, Viviana Domínguez, Roberto M Carrasco-Navarro, Maria E Diaz, Raúl E Velarde-López

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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  8. Kaiso Expression in Triple Negative Breast Cancer in a Tertiary Hospital in Ghana.Nigerian medical journal : journal of the Nigeria Medical Association
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Alejandro YábarDepartment of Pathology, Edgardo Rebagliatti Martins National Hospital, Lima, Perú.
Rosa MeléndezDepartment of Pathology, Guillermo Almenara Irigoyen National Hospital, Lima, Perú.
Silvia MuñozDepartment of Pathology, Alberto Sabogal National Hospital, Lima, Perú.
Hugo DeneoLaboratory of Pathological Anatomy, Nacional Cancer Institute, Montevideo, Uruguay.
Jimena FreireLaboratory of Pathological Anatomy, Nacional Cancer Institute, Montevideo, Uruguay.
Viviana DomínguezLaboratory of Pathological Anatomy, Nacional Cancer Institute, Montevideo, Uruguay.
Roberto M Carrasco-NavarroF. Hoffmann-La Roche Ltd., Lima, Perú.
Maria E DiazF. Hoffmann-La Roche Ltd., Lima, Perú.
Raúl E Velarde-LópezF. Hoffmann-La Roche Ltd., Lima, Perú.
Roche (Switzerland) · CHHospital Base Guillermo Almenara Irigoyen · PESt Martins Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is a heterogeneous disease composed of four main subtypes with distinct clinical and epidemiological features. Although several reports have described the distribution of BC subtypes in Latin America, the majority of them have not included the cellular marker, Ki-67, in the immunohistochemical (IHC) panel. The aim of the present study was to describe the distribution of BC subtypes in a cohort of Latin American women using an IHC panel with Ki-67. A prospective cohort of 580 patients in three centers of Peru (the Hospital Nacional Edgardo Rebagliatti Martins, the Hospital Nacional Guillermo Almenara Irigoyen, the Hospital Nacional Alberto Sabogal, Lima) and one in Uruguay (Instituto Nacional del Cáncer, Montevideo) were evaluated. BC phenotypes were classified according to an IHC panel: Estrogen receptor (ER), progesterone receptor (PgR), HER2 and Ki-67. Silver

Indexed as

breast cancer subtypesbreast neoplasmepidemiologyimmunohistochemistry

Identifiers

PMID28413656
PMCPMC5374902
OpenAlexW2593973016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.