Evidence map›Paper›PMID 28413648›Full record

ArticleBiomedical reports2017

Effects of hyperbaric oxygen treatment on gastric cancer cell line SGC7901.

Yinliang Qi, Jianfeng Ruan, Mei Wang, Yuanchang Dai, Qing Zhou, Shuyu Gui, Sumei Zhang, Yuan Wang

Open access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yinliang QiGeneral Department of Hyperbaric Oxygen, The Second People's Hospital of Hefei, Hefei, Anhui 230011, P.R. China.
Jianfeng RuanGeneral Department of Hyperbaric Oxygen, The Second People's Hospital of Hefei, Hefei, Anhui 230011, P.R. China.
Mei WangGeneral Department of Hyperbaric Oxygen, The Second People's Hospital of Hefei, Hefei, Anhui 230011, P.R. China.
Yuanchang DaiGeneral Department of Hyperbaric Oxygen, The Second People's Hospital of Hefei, Hefei, Anhui 230011, P.R. China.
Qing ZhouLaboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Shuyu GuiDepartment of Respiratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230011, P.R. China.
Sumei ZhangLaboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Yuan WangLaboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Third People's Hospital of Hefei · CNAnhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperbaric oxygen (HBO) has been previously identified as an effective adjunct treatment option for the management of brain injury, diabetic ulcers and chronic wounds. However, the roles of HBO as an adjunctive therapy for tumors remain controversial. The present research project was performed to explore the effects of HBO treatment on proliferation, autophagy and endoplasmic reticulum stress response of the gastric cancer cell line, SGC7901. The present study demonstrated that, after subjecting SGC7901 cells to HBO treatment, the increase in cell proliferation was significant, compared with that of the control group. In addition, there was a significant increase in LC3-phosphatidylethanolamine conjugate (LC3-II) level, as well as binding immunoglobulin protein level, and a significant decrease in CCAAT-enhancer-binding protein homologous protein level. These suggested that hyperbaric oxygen treatment alone may promote proliferation and cell survival of gastric cancer cell SGC7901, and inhibit apoptosis through regulating cell autophagy and oxidative stress.

Indexed as

gastric cancerhyperbaric oxygenSGC7901

Identifiers

PMID28413648
PMCPMC5374952
OpenAlexW2592477404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.