Evidence map›Paper›PMID 28413325›Full record

ArticleJournal of ginseng research2017

The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative-hypnotic, antistress, anxiolytic, and cognitive effects.

Irene Joy I Dela Peña, Hee Jin Kim, Chrislean Jun Botanas, June Bryan de la Peña, Thi Hong Van Le, Minh Duc Nguyen, Jeong Hill Park, Jae Hoon Cheong

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Irene Joy I Dela PeñaUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Nowon-gu, Seoul, Korea.
Hee Jin KimUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Nowon-gu, Seoul, Korea.
Chrislean Jun BotanasUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Nowon-gu, Seoul, Korea.
June Bryan de la PeñaUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Nowon-gu, Seoul, Korea.
Thi Hong Van LeSchool of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Minh Duc NguyenSchool of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Jeong Hill ParkFaculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Jae Hoon CheongUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, Nowon-gu, Seoul, Korea.
Sahmyook University · KRSeoul National University · KRTon Duc Thang University · VNUniversity of Medicine and Pharmacy at Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsVG extract (VGE) was orally administered to mice at various dosages to evaluate its psychomotor (open-field and rota-rod tests), sedative-hypnotic (pentobarbital-induced sleeping test), antistress (cold swimming test), anxiolytic (elevated plus-maze test), and cognitive (Y-maze and passive-avoidance tests) effects.

resultsVGE treatment increased the spontaneous locomotor activity, enhanced the endurance to stress, reduced the anxiety-like behavior, and ameliorated the scopolamine-induced memory impairments in mice. In addition, VGE treatment did not alter the motor balance and coordination of mice and did not potentiate pentobarbital-induced sleep, indicating that VGE has no sedative-hypnotic effects. The effects of VGE were comparable to those of the Korean Red Ginseng extract.

conclusionVG, like other ginseng products, has significant and potentially useful psychopharmacological effects. This includes, but is not limited to, psychomotor stimulation, anxiolytic, antistress, and memory enhancing effects.

Indexed as

antifatiguememoryPanax vietnamensispsychopharmacological activityVietnamese ginseng

Identifiers

PMID28413325
PMCPMC5386119
OpenAlexW2300438836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.