Evidence map›Paper›PMID 28413323›Full record

ArticleJournal of ginseng research2017

Preventive effect of fermented black ginseng against cisplatin-induced nephrotoxicity in rats.

Kiwon Jung, Jun Min An, Dae-Woon Eom, Ki Sung Kang, Su-Nam Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Nephroprotective Effect of BlackMolecules (Basel, Switzerland) · 2026
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  8. Cisplatin chemotherapy and renal function.Advances in cancer research · 2021
    Review
  9. Article
  10. Article
  11. Veterinary world · 2019
    Article
  12. Article
  13. Review
  14. All-trans retinoic acid prevents cisplatin-induced nephrotoxicity in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2019
    Article
  15. Fermentation of red ginseng extract by the probioticJournal of ginseng research · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Kiwon JungCollege of Pharmacy, CHA University, Pocheon, Korea.
Jun Min AnGINSENG BY PHARM Co., Ltd., Wonju, Korea.
Dae-Woon EomDepartment of Pathology, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam, Korea.
Su-Nam KimNatural Products Research Institute, Korea Institute of Science and Technology, Gangneung, Korea.
CHA University · KRGachon University · KRKorea Institute of Science and Technology · KRKorean Society of Ginseng · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFermented black ginseng (FBG) is processed ginseng by the repeated heat treatment and fermentation of raw ginseng. The protective effect and mechanism of FBG on cisplatin-induced nephrotoxicity was investigated to evaluate its therapeutic potential.

methodsThe free radical scavenging activity of FBG was measured using 1,1-diphenyl-2-picrylhydrazyl (DPPH). In addition, the protective effect against cisplatin-induced renal damage was tested in rats. FBG was orally administered every day at a dose of 150 mg/kg body weight for 10 d, and a single dose of cisplatin was administered intraperitoneally (7.5 mg/kg body weight) with 0.9% saline on the 4

resultsThe DPPH radical-scavenging activity of FBG (IC

conclusionThese results collectively show that the therapeutic evidence for FBG ameliorates the nephrotoxicity via regulating oxidative stress, inflammation, and apoptosis.

Indexed as

cisplatinfermented black ginsengoxidative stressPanax ginsengrenal damage

Identifiers

PMID28413323
PMCPMC5386130
OpenAlexW2295669014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.