Evidence map›Paper›PMID 28413315›Full record

ArticleJournal of ginseng research2017

The involvement of ginseng berry extract in blood flow via regulation of blood coagulation in rats fed a high-fat diet.

Min Hee Kim, Jongsung Lee, Sehyun Jung, Joo Wan Kim, Jae-Ho Shin, Hae-Jeung Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Pharmacological Activities forFoods (Basel, Switzerland) · 2021
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  5. Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Min Hee KimDepartment of Physical Therapy, College of Health Science, Eulji University, Gyeonggi-do, Korea.
Jongsung LeeDepartment of Genetic Engineering, College of Biotechnology and Bioengineering, Sungkyunkwan University, Gyeonggi-do, Korea.
Sehyun JungDepartment of Food and Nutrition, College of BioNano Technology, Gachon University, Gyeonggi-do, Korea.
Joo Wan KimNatural Product Research Center, Aribio Co. Ltd., Gyoenggi-do, Korea.
Jae-Ho ShinDepartment of Biomedical Laboratory Science, College of Health Science, Eulji University, Gyeonggi-do, Korea.
Hae-Jeung LeeDepartment of Food and Nutrition, College of BioNano Technology, Gachon University, Gyeonggi-do, Korea.
Eulji University · KRGachon University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study investigated the effect of ginseng berry hot water extract (GBx) on blood flow via the regulation of lipid metabolites and blood coagulation in rats fed a high-fat diet (HFD).

methodsSixty rats were divided into five groups in descending order of body weight. Except for the control group, the other four groups were fed a HFD containing 45% kcal from fat for 11 wk without GBx. GBx groups were then additionally treated by gastric gavage with GBx dissolved in distilled water at 50 (GBx 50) mg/kg, 100 (GBx 100) mg/kg, or 150 (GBx 150) mg/kg body weight for 6 wk along with the HFD. To investigate the effects of GBx on rats fed a HFD, biochemical metabolite, blood coagulation assay, and histological analysis were performed.

resultsIn the experiments to measure the serum levels of leptin and apolipoprotein B/A, GBx treatment attenuated the HFD-induced increases in these metabolites (

conclusionThese results suggest the possibility that GBx can ameliorate blood flow by decreasing intima-media thickness via the regulation of blood coagulation factors related to lipid metabolites in rats fed a HFD.

Indexed as

blood coagulationblood flowginseng berryhigh-fat dietlipid metabolite

Identifiers

PMID28413315
PMCPMC5386124
OpenAlexW2275737117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.