Evidence map›Paper›PMID 28413159›Full record

ArticleGenetics2017

The Hippo Pathway Maintains the Equatorial Division Plane in the Ciliate

Yu-Yang Jiang, Wolfgang Maier, Ralf Baumeister, Gregory Minevich, Ewa Joachimiak, Zheng Ruan, Natarajan Kannan, Diamond Clarke, Joseph Frankel, Jacek Gaertig

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Big1 is a cell cycle regulator linking cell size to basal body number.bioRxiv : the preprint server for biology · 2025
    Article
  2. Article
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  5. Article
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  8. TheMolecular biology of the cell · 2023
    Article
  9. Article
  10. Anterior-posterior pattern formation in ciliates.The Journal of eukaryotic microbiology · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Polarity in Ciliate Models: From Cilia to Cell Architecture.Frontiers in cell and developmental biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Yu-Yang JiangDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.
Wolfgang MaierBio3/Bioinformatics and Molecular Genetics (Faculty of Biology) and ZMBZ (Faculty of Medicine).
Ralf BaumeisterBio3/Bioinformatics and Molecular Genetics (Faculty of Biology) and ZMBZ (Faculty of Medicine).
Gregory MinevichDepartment of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, New York 10032.
Ewa JoachimiakLaboratory of Cytoskeleton and Cilia Biology, Department of Cell Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, 02-093 Warsaw, Poland.
Zheng RuanInstitute of Bioinformatics, University of Georgia, Athens, Georgia 30602.
Natarajan KannanInstitute of Bioinformatics, University of Georgia, Athens, Georgia 30602.
Diamond ClarkeDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.
Joseph FrankelDepartment of Biology, University of Iowa, Iowa City, Iowa 52242.
Jacek GaertigDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602 jgaertig@uga.edu.
University of Georgia · USColumbia University Irving Medical Center · USInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLUniversity of Freiburg · DEUniversity of Iowa · US

Funding

Identifying genes that turn skin cells into neuronsF31NS074841 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MINEVICH, GREGORY · 2011 to 2013
$126k
NINDS NIH HHS F31 NS074841
6 · The paper itself

Abstract

The mechanisms that govern pattern formation within the cell are poorly understood. Ciliates carry on their surface an elaborate pattern of cortical organelles that are arranged along the anteroposterior and circumferential axes by largely unknown mechanisms. Ciliates divide by tandem duplication: the cortex of the predivision cell is remodeled into two similarly sized and complete daughters. In the conditional

Indexed as

Cell CycleCell Cycle ProteinsCell DivisionCytokinesisMorphogenesisProtozoan ProteinsSignal TransductionTetrahymena thermophilaCell Cycle ProteinsProtozoan ProteinsciliatecytokinesisHippopolarityTetrahymena

Identifiers

PMID28413159
PMCPMC5499192
OpenAlexW2606781414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.