Evidence map›Paper›PMID 28412970›Full record

ArticleBMC systems biology2017

Membrane potential independent transport of NH

Hugo F Cueto-Rojas, Nicholas Milne, Ward van Helmond, Mervin M Pieterse, Antonius J A van Maris, Jean-Marc Daran, S Aljoscha Wahl

Open access · diamondAbstract read
In one paragraph

Article in BMC systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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  7. First report on Vitamin BBiotechnology for biofuels and bioproducts · 2022
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  11. Review
  12. InAntioxidants (Basel, Switzerland) · 2020
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  13. Article
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  15. Metabolic switches from quiescence to growth in synchronized Saccharomyces cerevisiae.Metabolomics : Official journal of the Metabolomic Society · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hugo F Cueto-RojasDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands.ORCID 0000-0001-9776-8064
Nicholas MilneDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands.
Ward van HelmondDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands.
Mervin M PieterseDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands.
Antonius J A van MarisDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands.
Jean-Marc DaranDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands. J.G.Daran@tudelft.nl.
S Aljoscha WahlDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629HZ, Delft, The Netherlands. S.A.Wahl@tudelft.nl.
Delft University of Technology · NLAlbaNova · SEEvolva (Denmark) · DKNetherlands Forensic Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial production of nitrogen containing compounds requires a high uptake flux and assimilation of the N-source (commonly ammonium), which is generally coupled with ATP consumption and negatively influences the product yield. In the industrial workhorse Saccharomyces cerevisiae, ammonium (NH

resultsTo decrease the ATP costs for nitrogen assimilation, the Mep genes were removed, resulting in a strain unable to uptake the NH

conclusionsOur results suggest that the uncharged species, NH

Indexed as

Gene DeletionMembrane PotentialsAdenosine TriphosphateAerobiosisAmmonium CompoundsBiological TransportCation Transport ProteinsDiffusionExtracellular SpaceHydrogen-Ion ConcentrationIntracellular SpaceMetabolomicsNitrogenPermeabilityProteomicsSaccharomyces cerevisiaeAdenosine TriphosphateAmmonium CompoundsCation Transport ProteinsNitrogenSaccharomyces cerevisiae ProteinsAmmonia passive diffusionAmmonium transportCentral nitrogen metabolismIntracellular ammoniumMetabolomicsThermodynamics

Identifiers

PMID28412970
PMCPMC5392931
OpenAlexW2606391719

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.