ArticleNeuroscience2018
Optogenetic stimulation of cortex to map evoked whisker movements in awake head-restrained mice.
Article in Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- The anterior cingulate cortex modulates pupil-linked arousal.Science advances · 2026Article
- Diversity in Whisking-Related Dynamics of Layer 5 Neurons in the Motor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Temporal dynamics between the whisker sensorimotor cortex and the olivocerebellar module in awake mice.Frontiers in cellular neuroscience · 2026Article
- Mesenchymal stem cells reverse disease-specific abnormalities in nociceptive regions of the brain.Brain communications · 2026Article
- Multiple cortical systems influence a single vibrissa muscle.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics.Frontiers in neural circuits · 2025Article
- Tactile processing in mouse cortex depends on action context.Cell reports · 2024Article
- Article
- Sparse and distributed cortical populations mediate sensorimotor integration.bioRxiv : the preprint server for biology · 2023Article
- Beyond body maps: Information content of specific body parts is distributed across the somatosensory homunculus.Cell reports · 2022Article
- Adaptive Whisking in Mice.Frontiers in systems neuroscience · 2021Article
- Distributed Motor Control of Limb Movements in Rat Motor and Somatosensory Cortex: The Sensorimotor Amalgam Revisited.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Cortico-Thalamo-Cortical Circuits of Mouse Forelimb S1 Are Organized Primarily as Recurrent Loops.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Sensory cortical control of movement.Nature neuroscience · 2020Article
- Article
- Sensorimotor processing in the rodent barrel cortex.Nature reviews. Neuroscience · 2019Review
- A spatially dynamic network underlies the generation of inspiratory behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Optogenetic study of the response interaction among multi-afferent inputs in the barrel cortex of rats.Scientific reports · 2019Article
- More than Just a "Motor": Recent Surprises from the Frontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Circuits in the rodent brainstem that control whisking in concert with other orofacial motor actions.Neuroscience · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whisker movements are used by rodents to touch objects in order to extract spatial and textural tactile information about their immediate surroundings. To understand the mechanisms of such active sensorimotor processing it is important to investigate whisker motor control. The activity of neurons in the neocortex affects whisker movements, but many aspects of the organization of cortical whisker motor control remain unknown. Here, we filmed whisker movements evoked by sequential optogenetic stimulation of different locations across the left dorsal sensorimotor cortex of awake head-restrained mice. Whisker movements were evoked by optogenetic stimulation of many regions in the dorsal sensorimotor cortex. Optogenetic stimulation of whisker sensory barrel cortex evoked retraction of the contralateral whisker after a short latency, and a delayed rhythmic protraction of the ipsilateral whisker. Optogenetic stimulation of frontal cortex evoked rhythmic bilateral whisker protraction with a longer latency compared to stimulation of sensory cortex. Compared to frontal cortex stimulation, larger amplitude bilateral rhythmic whisking in a less protracted position was evoked at a similar latency by stimulating a cortical region posterior to Bregma and close to the midline. These data suggest that whisker motor control might be broadly distributed across the dorsal mouse sensorimotor cortex. Future experiments must investigate the complex neuronal circuits connecting specific cell-types in various cortical regions with the whisker motor neurons located in the facial nucleus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.