Evidence map›Paper›PMID 28412240›Full record

Trial reportLife sciences2017

The level of effort, rather than muscle exercise intensity determines strength gain following a six-week training.

Chang-Hao Jiang, Vinoth K Ranganathan, Vlodek Siemionow, Guang H Yue

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Chang-Hao JiangBeijing Key Lab of Physical Fitness Evaluation and Tech Analysis, Capital University of Physical Education and Sports, 100191 Beijing, China.
Vinoth K RanganathanDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, United States.
Vlodek SiemionowDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, United States.
Guang H YueDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, United States; Human Performance and Engineering Research, Kessler Foundation, West Orange, NJ 07052, United States; Department of Physical Medicine & Rehabilitation, Rutgers New Jersey Medical School, Rutgers University, Newark, NJ 07103, United States. Electronic address: gyue@kesslerfoundation.org.
Cleveland Clinic Lerner College of Medicine · USCapital University of Physical Education and Sports · CNKessler Foundation · US

Funding

Neurophysiological Evaluation of Training Effect on Cancer-Related WeaknessR01CA189665 · NCI · KESSLER FOUNDATION, INC. · PI YUE, GUANG H · 2014 to 2019
$2.0M
MENTAL TRAINING EFFECTS ON VOLUNTARY MUSCLE STRENGTHR01NS035130 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI YUE, GUANG H · 1997 to 2012
$1.7M
NCI NIH HHS R01 CA189665NINDS NIH HHS R01 NS035130
6 · The paper itself

Abstract

aimThis study investigated the effect of voluntary motor effort during a low-intensity (30% maximal voluntary contraction [MVC]) muscle exercise training program on increasing muscle strength. MATERIALS AND

methodsEighteen young and healthy individuals were randomly assigned to one of three groups: high mental effort (HME), low mental effort (LME), or a no-training control (CTRL) group. Training lasted for 6weeks (15min/day, 5days/week). The participants' right-elbow flexor muscle strength was measured before and after the training program. KEY

findingsAfter training, the HME group gained 20.47±8.33% (P=0.01) strength while the LME and CTRL groups had negligible strength changes (1.89±0.96% and -3.27±2.61%, respectively; P>0.05) despite muscle contraction intensity (30% MVC) sustained during training was the same for the HME and LME groups. These results suggest that the level of effort involved in resistance exercise training plays a critical role in determining the amount of strength augmentation. SIGNIFICANCE: The finding that high effort combined with low-level physical exercise training can significantly increase muscle strength has rehabilitation applications as many patients and frail older adults have difficulties in participating in high-intensity exercise training such as lifting heavy weights. High effort plus low-level muscle exercise might serve as a safe training regimen for effective muscle strengthening in vulnerable populations.

Indexed as

AdolescentAdultExerciseHumansMuscle ContractionMuscle, SkeletalMuscle StrengthPhysical ExertionPilot ProjectsResistance TrainingYoung AdultElbow flexor musclesExercise intensityMaximal voluntary contraction (MVC)Mental effort trainingMuscle strength

Identifiers

PMID28412240
PMCPMC6067674
OpenAlexW2605775989

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.