ArticleJournal of critical care2017
Managing sepsis: Electronic recognition, rapid response teams, and standardized care save lives.
Article in Journal of critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sepsis Alerts in Emergency Departments: A Systematic Review of Accuracy and Quality Measure Impact.The western journal of emergency medicine · 2020Pooled it
- Digital Alerting and Outcomes in Patients With Sepsis: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2019Pooled it
- Real-Time Emergency Department Electronic Notifications Regarding High-Risk Patients: A Systematic Review.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2019Pooled it
- Admission CRP as an Independent Predictor of Prolonged Length of Stay in Calculous Acute Pyelonephritis: A Comparative Evaluation With the HALP Score.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026.Intensive care medicine · 2026Article
- Direct admission to the intensive care unit for patients with prehospital septic shock is associated with a lower 30-day mortality rate.Scientific reports · 2026Article
- Impact of the implementation of an obstetric sepsis protocol on maternal and neonatal outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- Understanding ICU Nursing Knowledge, Perceived Barriers, and Facilitators of Sepsis Recognition and Management: A Cross-Sectional Study.Critical care explorations · 2025Article
- Views and Uses of Sepsis Digital Alerts in National Health Service Trusts in England: Qualitative Study With Health Care Professionals.JMIR human factors · 2024Article
- Article
- Association between prehospital ROX index with 30-day mortality among septic shock.European journal of medical research · 2024Article
- Sepsis screening protocol implementation: a clinician-validated rapid realist review.BMJ open quality · 2024Review
- The prehospital NEW score to assess septic shock in-hospital, 30-day and 90-day mortality.BMC infectious diseases · 2024Article
- A nursing-led sepsis response team guiding resuscitation with point-of-care ultrasound: A review and model for improving bundle compliance while individualizing sepsis care.SAGE open medicine · 2024Review
- Prehospital pulse pressure and mortality of septic shock patients cared for by a mobile intensive care unit.BMC emergency medicine · 2023Article
- Epic Sepsis Model Inpatient Predictive Analytic Tool: A Validation Study.Critical care explorations · 2023Article
- Association of Early Serum Phosphate Levels and Mortality in Patients with Sepsis.The western journal of emergency medicine · 2023Article
- Mortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study.Critical care (London, England) · 2022Article
- Effectiveness of automated alerting system compared to usual care for the management of sepsis.NPJ digital medicine · 2022Article
- Association between prehospital shock index variation and 28-day mortality among patients with septic shock.BMC emergency medicine · 2022Article
Corrections and comments
- Commented on byManaging sepsis.2018
Authors and funding
15 authors.
Funding
Abstract
purposeSepsis can lead to poor outcomes when treatment is delayed or inadequate. The purpose of this study was to evaluate outcomes after initiation of a hospital-wide sepsis alert program. MATERIALS AND
methodsRetrospective review of patients ≥18years treated for sepsis.
resultsThere were 3917 sepsis admissions: 1929 admissions before, and 1988 in the after phase. Mean age (57.3 vs. 57.1, p=0.94) and Charlson Comorbidity Scores (2.52 vs. 2.47, p=0.35) were similar between groups. Multivariable analyses identified significant reductions in the after phase for odds of death (OR 0.62, 95% CI 0.39-0.99, p=0.046), mean intensive care unit LOS (2.12days before, 95%CI 1.97, 2.34; 1.95days after, 95%CI 1.75, 2.06; p<0.001), mean overall hospital LOS (11.7days before, 95% CI 10.9, 12.7days; 9.9days after, 95% CI 9.3, 10.6days, p<0.001), odds of mechanical ventilation use (OR 0.62, 95% CI 0.39, 0.99, p=0.007), and total charges with a savings of $7159 per sepsis admission (p=0.036). There was no reduction in vasopressor use (OR 0.89, 95% CI 0.75, 0.1.06, p=0.18).
conclusionA hospital-wide program utilizing electronic recognition and RRT intervention resulted in improved outcomes in patients with sepsis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.