Evidence map›Paper›PMID 28411832›Full record

ArticleThe Journal of investigative dermatology2017

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Associations, Outcomes, and Pathobiology-Thirty Years of Progress but Still Much to Be Done.

Robert S Stern, Sherrie J Divito

Abstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Necroptosis in SJS/TEN:Current issues in molecular biology · 2026
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  13. Multidisciplinary Treatment in Toxic Epidermal Necrolysis.International journal of environmental research and public health · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Toxic epidermal necrosis associated with phenobarbitone: a case report and brief review of the literatures.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Robert S SternBeth Israel Deaconess Medical, Boston, Massachusetts, USA. Electronic address: rstern@bidmc.harvard.edu.
Sherrie J DivitoBrigham and Women's Hospital Ringgold Standard Institution-Dermatology, Boston, Massachusetts, USA.

Funding

Investigating a novel cell population in delayed-onset drug hypersensitivity reactionsDP5OD023091 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI DIVITO, SHERRIE JILL · 2016 to 2020
$2.1M
NIH HHS DP5 OD023091
6 · The paper itself

Abstract

Although rare, Stevens-Johnson syndrome and toxic epidermal necrolysis remain among the most devastating of acute conditions involving the skin. In the past 30 years, tremendous progress has been made in understanding the causes and pathobiology of this often life-threatening condition. Su et al demonstrate associations between IL 15 serum levels and the outcome of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. Their findings provide ideas for further investigations that may help us better understand the role of cytokines in this T-cell mediate disease and provides clues to possible new therapies.

Indexed as

Acute DiseaseStevens-Johnson SyndromeCytokinesHumansInterleukin-15SkinCytokinesInterleukin-15

Identifiers

PMID28411832
PMCPMC5567821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.