Evidence map›Paper›PMID 28411288›Full record

Observational studyJournal of hospital medicine2017

Predicting 30-Day Pneumonia Readmissions Using Electronic Health Record Data.

Anil N Makam, Oanh Kieu Nguyen, Christopher Clark, Song Zhang, Bin Xie, Mark Weinreich, Eric M Mortensen, Ethan A Halm

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of hospital medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Predicting the 14-Day Hospital Readmission of Patients with Pneumonia Using Artificial Neural Networks (ANN).International journal of environmental research and public health · 2021
    Article
  9. Article
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  13. Associations between biomarkers at discharge and co-morbidities and risk of readmission after community-acquired pneumonia: a retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anil N MakamDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Oanh Kieu NguyenDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Christopher ClarkOffice of Research Administration, Parkland Health and Hospital System, Dallas, Texas, USA.
Song ZhangDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bin XieParkland Center for Clinical Innovation, Dallas, Texas, USA.
Mark WeinreichDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Eric M MortensenDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ethan A HalmDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
The University of Texas Southwestern Medical Center · USParkland Center For Clinical Innovation · USParkland Health & Hospital System · USVA North Texas Health Care System · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1KL2TR001103 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$4.0M
AHRQ HHS R24 HS022418NCATS NIH HHS KL2 TR001103NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

backgroundReadmissions after hospitalization for pneumonia are common, but the few risk-prediction models have poor to modest predictive ability. Data routinely collected in the electronic health record (EHR) may improve prediction.

objectiveTo develop pneumonia-specific readmission risk-prediction models using EHR data from the first day and from the entire hospital stay ("full stay").

designObservational cohort study using stepwise-backward selection and cross-validation. SUBJECTS: Consecutive pneumonia hospitalizations from 6 diverse hospitals in north Texas from 2009-2010. MEASURES: All-cause nonelective 30-day readmissions, ascertained from 75 regional hospitals.

resultsOf 1463 patients, 13.6% were readmitted. The first-day pneumonia-specific model included sociodemographic factors, prior hospitalizations, thrombocytosis, and a modified pneumonia severity index; the full-stay model included disposition status, vital sign instabilities on discharge, and an updated pneumonia severity index calculated using values from the day of discharge as additional predictors. The full-stay pneumonia-specific model outperformed the first-day model (C statistic 0.731 vs 0.695; P = 0.02; net reclassification index = 0.08). Compared to a validated multi-condition readmission model, the Centers for Medicare and Medicaid Services pneumonia model, and 2 commonly used pneumonia severity of illness scores, the full-stay pneumonia-specific model had better discrimination (C statistic range 0.604-0.681; P < 0.01 for all comparisons), predicted a broader range of risk, and better reclassified individuals by their true risk (net reclassification index range, 0.09-0.18).

conclusionsEHR data collected from the entire hospitalization can accurately predict readmission risk among patients hospitalized for pneumonia. This approach outperforms a first-day pneumonia-specific model, the Centers for Medicare and Medicaid Services pneumonia model, and 2 commonly used pneumonia severity of illness scores. Journal of Hospital Medicine 2017;12:209-216.

Indexed as

HospitalizationModels, StatisticalPneumoniaElectronic Health RecordsHumansPatient ReadmissionRetrospective StudiesSeverity of Illness IndexTexas

Identifiers

PMID28411288
PMCPMC6296251
OpenAlexW2606022689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.