Evidence map›Paper›PMID 28411256›Full record

ArticleHaematologica2017

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.

Giulia Daniele, Giorgia Simonetti, Caterina Fusilli, Ilaria Iacobucci, Angelo Lonoce, Antonio Palazzo, Mariana Lomiento, Fabiana Mammoli, Renè Massimiliano Marsano, Elena Marasco and 16 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 7 institutions in 2 countries.

Giulia DanieleDepartment of Biology, University of Bari "A. Moro", Italy.
Giorgia SimonettiDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Caterina FusilliIRCCS Casa Sollievo della Sofferenza, Bioinformatics Unit, San Giovanni Rotondo, Italy.
Ilaria IacobucciDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Angelo LonoceDepartment of Biology, University of Bari "A. Moro", Italy.
Antonio PalazzoDepartment of Biology, University of Bari "A. Moro", Italy.
Mariana LomientoDepartment of Life Science, University of Modena and Reggio Emilia, Modena, Italy.
Fabiana MammoliDepartment of Life Science, University of Modena and Reggio Emilia, Modena, Italy.
Renè Massimiliano MarsanoDepartment of Biology, University of Bari "A. Moro", Italy.
Elena MarascoDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Vilma MantovaniCenter for Applied Biomedical Research (CRBA), S. Orsola-Malpighi Hospital, Bologna, Italy.
Hilmar QuentmeierLeibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany.
Hans G DrexlerLeibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany.
Jie DingLeibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany.
Orazio PalumboMedical Genetics Unit, IRCCS "Casa Sollievo della Sofferenza (CSS)" Hospital, San Giovanni Rotondo, Italy.
Massimo CarellaMedical Genetics Unit, IRCCS "Casa Sollievo della Sofferenza (CSS)" Hospital, San Giovanni Rotondo, Italy.
Niroshan NadarajahMLL Münchner Leukämielabor GmbH, München, Germany.
Margherita PerriconeDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Emanuela OttavianiDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Carmen BaldazziDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Nicoletta TestoniDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Cristina PapayannidisDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Sergio FerrariDepartment of Life Science, University of Modena and Reggio Emilia, Modena, Italy.
Tommaso MazzaIRCCS Casa Sollievo della Sofferenza, Bioinformatics Unit, San Giovanni Rotondo, Italy.
Giovanni MartinelliDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.
Clelia Tiziana StorlazziDepartment of Biology, University of Bari "A. Moro", Italy cleliatiziana.storlazzi@uniba.it.
University of Bologna · ITUniversity of Bari Aldo Moro · ITCasa Sollievo della Sofferenza · ITLeibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures · DEUniversity of Modena and Reggio Emilia · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMunich Leukemia Laboratory (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We here describe a leukemogenic role of the homeobox gene

Indexed as

Ectopic Gene ExpressionEpigenesis, GeneticAdultAgedAged, 80 and overBiomarkers, TumorCell DifferentiationCell Line, TumorCell ProliferationComputational BiologyDatabases, GeneticDNA (Cytosine-5-)-MethyltransferasesDNA MethylationDNA Methyltransferase 3AFemaleGene Expression ProfilingBiomarkers, TumorDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanHomeodomain ProteinsNPM1 protein, humanNucleophosmin

Identifiers

PMID28411256
PMCPMC5566027
OpenAlexW2605453530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.