ArticleJournal of the American Heart Association2017
Characteristics of Earlier Versus Delayed Presentation of Very Late Drug-Eluting Stent Thrombosis: An Optical Coherence Tomographic Study.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Pathogenesis of plaque erosion.Trends in cardiovascular medicine · 2026Review
- Intravascular Imaging for Facilitated Coronary Interventions in DES Era.Journal of cardiovascular development and disease · 2026Review
- Neoatherosclerosis: A Distinctive Pathological Mechanism of Stent Failure.Reviews in cardiovascular medicine · 2024Review
- Impact of diabetes mellitus on the early-phase arterial healing after drug-eluting stent implantation.Cardiovascular diabetology · 2020Observational
- Association of ABO blood groups and non-culprit plaque characteristics in acute coronary syndrome: an optical coherence tomography study.Annals of translational medicine · 2020Article
- Drug-eluting coronary stents: insights from preclinical and pathology studies.Nature reviews. Cardiology · 2020Review
- Neoatherosclerosis - Long-Term Assessment of Bioresorbable Vascular Scaffold.Circulation reports · 2019Review
- Differences between first-generation and second-generation drug-eluting stent regarding in-stent neoatherosclerosis characteristics: an optical coherence tomography analysis.The international journal of cardiovascular imaging · 2018Article
- Formation and Transformation of Neointima after Drug-eluting Stent Implantation: Insights from Optical Coherence Tomographic Studies.Korean circulation journal · 2017Review
Corrections and comments
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Authors and funding
19 authors at 12 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pathophysiology underlying very late drug-eluting stent (DES) thrombosis is not sufficiently understood. Using optical coherence tomography, we investigated characteristics of very late stent thrombosis (VLST) according to different onset times. METHODS AND
resultsA total of 98 patients from 10 South Korean hospitals who underwent optical coherence tomography for evaluation of very late DES thrombosis were retrospectively included in analyses. VLST occurred at a median of 55.1 months after DES implantation. All patients were divided into 2 equal groups of earlier versus delayed presentation of VLST, according to median onset time. In total, 27 patients were treated with next-generation DES and 71 with first-generation DES. Based on optical coherence tomography findings at thrombotic sites, main VLST mechanisms were as follows, in descending order: neoatherosclerosis (34.7%), stent malapposition (33.7%), and uncovered struts without stent malapposition or evagination (24.5%). Compared with patients with earlier VLST, patients with delayed VLST had lower frequency of uncovered struts without stent malapposition or evagination (34.7% versus 14.3%, respectively;
conclusionsThe pathological mechanisms of very late DES thrombosis changed over time. Delayed neointimal healing remained a substantial substrate for VLST, even long after DES implantation.
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