Evidence map›Paper›PMID 28410610›Full record

ArticleMalaria journal2017

An intricate case of multidrug resistant Plasmodium falciparum isolate imported from Cambodia.

Raffaele Dell'Acqua, Claudia Fabrizio, Francesco Di Gennaro, Sergio Lo Caputo, Annalisa Saracino, Michela Menegon, Mariangela L'Episcopia, Carlo Severini, Laura Monno, Francesco Castelli and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Artemisinin resistance: an important emerging clinical problem in tropical medicine.International journal of physiology, pathophysiology and pharmacology · 2021
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Raffaele Dell'AcquaClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy. dellacqua.raffaele@gmail.com.ORCID http://orcid.org/0000-0003-1058-505X
Claudia FabrizioClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
Francesco Di GennaroClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
Sergio Lo CaputoClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
Annalisa SaracinoClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
Michela MenegonDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Mariangela L'EpiscopiaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Carlo SeveriniDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Laura MonnoClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
Francesco CastelliUniversity Department of Infectious and Tropical Diseases, Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Italy.
Gioacchino AngaranoClinic of Infectious Diseases, Università degli Studi di Bari Aldo Moro, Piazza G. Cesare, 11, 70124, Bari, Italy.
University of Bari Aldo Moro · ITIstituto Superiore di Sanità · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImported cases of multidrug resistant Plasmodium falciparum and treatment failure with artemisinin-based regimens, although rare, have been described also in Western countries and their management is often challenging. This is also due to an inadequate knowledge and implementation of health prevention measures. CASE REPORT: A complex case of imported malaria caused by Plasmodium vivax/P. falciparum isolates in a patient who was not taking chemoprophylaxis while he was travelling in Cambodia is reported in this article. After failures of artemisinin-based and both oral and intravenous quinine-based regimens, a multidrug resistant P. falciparum was detected. The patient was successfully treated with atovaquone-proguanil.

conclusionsThis experience highlights the importance of a careful management that should be based not only on the most up-to-date guidelines, but also on the awareness of a rapidly evolving scenario.

Indexed as

Drug Resistance, MultipleTravelAdultArtemisininsAtovaquoneCambodiaCoinfectionDrug CombinationsHumansLactonesMalariaMalePlasmodium falciparumPlasmodium vivaxProguanilQuinineartemisinArtemisininsAtovaquoneatovaquone, proguanil drug combinationDrug CombinationsLactonesProguanilQuinineAntimalarialsCambodiaDrug resistanceGenes, MDRMalariaMalaria, FalciparumMalaria, VivaxMultipleTravel medicine

Identifiers

PMID28410610
PMCPMC5391556
OpenAlexW2606281194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.