Evidence map›Paper›PMID 28410483›Full record

ArticleVirology2017

Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection.

Caitlyn T Molloy, Jennifer S Andonian, Harrison M Seltzer, Megan C Procario, Michael E Watson, Jason B Weinberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Considerations of CD8Frontiers in immunology · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Caitlyn T MolloyDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, USA.
Jennifer S AndonianSchool of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Harrison M SeltzerDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, USA.
Megan C ProcarioDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Michael E WatsonDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, USA.
Jason B WeinbergDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, USA; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: jbwein@umich.edu.
University of Michigan · US

Funding

Modulation of adenovirus pathogenesis by prostaglandin E2R01AI083334 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEINBERG, JASON BRICE · 2010 to 2014
$1.9M
Adenovirus myocarditis: defining host factors contributing to pathogenesisR21AI103452 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEINBERG, JASON BRICE · 2013 to 2014
$414k
NIAID NIH HHS R01 AI083334NIAID NIH HHS R21 AI103452
6 · The paper itself

Abstract

CD8 T cells are key components of the immune response to viruses, but their roles in the pathogenesis of adenovirus respiratory infection have not been characterized. We used mouse adenovirus type 1 (MAV-1) to define CD8 T cell contributions to the pathogenesis of adenovirus respiratory infection. CD8 T cell deficiency in β2m

Indexed as

Adenoviridae InfectionsAnimalsCD8-Positive T-LymphocytesFemaleInterferon-gammaInterleukin-10LungMaleMastadenovirusMiceMice, Inbred C57BLPerforinRodent DiseasesVirus ReplicationInterferon-gammaInterleukin-10PerforinAdenovirusCD8 T cellsInterferon gammaPerforinRespiratory infection

Identifiers

PMID28410483
PMCPMC5493992
OpenAlexW2605852165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.