Evidence map›Paper›PMID 28410426›Full record

ArticlePloS one2017

Factors affecting human colostrum fatty acid profile: A case study.

Vassilia J Sinanoglou, Dionisis Cavouras, Theodora Boutsikou, Despina D Briana, Dimitra Z Lantzouraki, Stella Paliatsiou, Paraskevi Volaki, Sotiris Bratakos, Ariadne Malamitsi-Puchner, Panagiotis Zoumpoulakis

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Molecular Reactivity in Maternal Pregnancy Blood and Neonatal Dried Blood Spots Is Associated with the Risk of Pediatric Acute Lymphoblastic Leukemia.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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  18. Gestational Diabetes Mellitus Changes the Metabolomes of Human Colostrum, Transition Milk and Mature Milk.Medical science monitor : international medical journal of experimental and clinical research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vassilia J SinanoglouLaboratory of Chemistry, Analysis & Design of Food Processes, Instrumental Food Analysis, Department of Food Technology, Technological Educational Institution of Athens, Greece.ORCID http://orcid.org/0000-0001-9348-6078
Dionisis CavourasMedical Image and Signal Processing Laboratory, Department of Biomedical Engineering, Technological Education Institution of Athens, Greece.
Theodora BoutsikouDepartment of Neonatology, National and Kapodistrian University of Athens, Medical School Aretaieio University Hospital, Athens, Greece.
Despina D BrianaDepartment of Neonatology, National and Kapodistrian University of Athens, Medical School Aretaieio University Hospital, Athens, Greece.
Dimitra Z LantzourakiLaboratory of Chemistry, Analysis & Design of Food Processes, Instrumental Food Analysis, Department of Food Technology, Technological Educational Institution of Athens, Greece.
Stella PaliatsiouDepartment of Neonatology, National and Kapodistrian University of Athens, Medical School Aretaieio University Hospital, Athens, Greece.
Paraskevi VolakiDepartment of Neonatology, National and Kapodistrian University of Athens, Medical School Aretaieio University Hospital, Athens, Greece.
Sotiris BratakosLaboratory of Chemistry, Analysis & Design of Food Processes, Instrumental Food Analysis, Department of Food Technology, Technological Educational Institution of Athens, Greece.
Ariadne Malamitsi-PuchnerDepartment of Neonatology, National and Kapodistrian University of Athens, Medical School Aretaieio University Hospital, Athens, Greece.
Panagiotis ZoumpoulakisInstitute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of maternal colostrum to infant development has been extensively studied and presented. Among the main factors which contribute to breast milk composition are maternal diet, age and body mass index, parity, duration of pregnancy and stage of lactation. This study aims to investigate the potential impact of several factors including demographic (i.e. maternal age and nationality) on the colostrum fatty acid profile. Colostrum was collected the third day postpartum in a Greek maternity hospital. Certain lipid quality indices and fatty acid ratios were estimated and results were statistically processed. The main identified fatty acids were palmitic (C16:0), oleic (C18:1ω-9), and linoleic (C18:2ω-6) acids. Among fatty acids, saturated fatty acids predominated (47.61%), followed by monounsaturated fatty acids (39.26%), while polyunsaturated fatty acids had the lowest proportion (13.13%). Values of lipid quality indices were within the reported in the literature ranges. Maternal body mass index, nationality, age, mode of delivery, gender and fetal weight percentile were studied in respect to their potential influence on the fatty acid profile of colostrum fat. Results suggest that colostrum fatty acid profile was mainly dependent on maternal nationality and age rather than mode of delivery and maternal BMI. Regarding the effect of maternal nationality, significant differences were found for saturated and monounsaturated fatty acids. Of the most interesting findings is that colostrum fat from older (≥35 years) mothers had less saturated fat and more appropriate LQIs values. Finally, a reversed correlation was observed between the customized centile of the infants and the colostrum fat content.

Indexed as

AdultAge FactorsBody Mass IndexChromatography, GasColostrumFatty AcidsFatty Acids, MonounsaturatedFemaleGestational AgeHumansInfant, NewbornLinoleic AcidMaleOleic AcidPalmitic AcidPregnancyFatty AcidsFatty Acids, MonounsaturatedLinoleic AcidOleic AcidPalmitic Acid

Identifiers

PMID28410426
PMCPMC5391953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.