Evidence map›Paper›PMID 28410419›Full record

Trial reportPloS one2017

The electrical heart axis and ST events in fetal monitoring: A post-hoc analysis following a multicentre randomised controlled trial.

Rik Vullings, Kim M J Verdurmen, Alexandra D J Hulsenboom, Stephanie Scheffer, Hinke de Lau, Anneke Kwee, Pieter F F Wijn, Isis Amer-Wåhlin, Judith O E H van Laar, S Guid Oei

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Rik VullingsDepartment of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Kim M J VerdurmenDepartment of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands.
Alexandra D J HulsenboomDepartment of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands.
Stephanie SchefferDepartment of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands.
Hinke de LauDepartment of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands.
Anneke KweeDepartment of Obstetrics and Gynaecology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Pieter F F WijnDepartment of Clinical Physics, Máxima Medical Centre, Veldhoven, the Netherlands.
Isis Amer-WåhlinDepartment of Women and Child Health, Karolinska Institute, Stockholm, Sweden.
Judith O E H van LaarDepartment of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, the Netherlands.
S Guid OeiDepartment of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Máxima Medisch Centrum · NLEindhoven University of Technology · NLKarolinska Institutet · SERadboud University Nijmegen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveReducing perinatal morbidity and mortality is one of the major challenges in modern health care. Analysing the ST segment of the fetal electrocardiogram was thought to be the breakthrough in fetal monitoring during labour. However, its implementation in clinical practice yields many false alarms and ST monitoring is highly dependent on cardiotocogram assessment, limiting its value for the prediction of fetal distress during labour. This study aims to evaluate the relation between physiological variations in the orientation of the fetal electrical heart axis and the occurrence of ST events.

methodsA post-hoc analysis was performed following a multicentre randomised controlled trial, including 1097 patients from two participating centres. All women were monitored with ST analysis during labour. Cases of fetal metabolic acidosis, poor signal quality, missing blood gas analysis, and congenital heart disease were excluded. The orientation of the fetal electrical heart axis affects the height of the initial T/QRS baseline, and therefore the incidence of ST events. We grouped tracings with the same initial baseline T/QRS value. We depicted the number of ST events as a function of the initial baseline T/QRS value with a linear regression model.

resultsA significant increment of ST events was observed with increasing height of the initial T/QRS baseline, irrespective of the fetal condition; correlation coefficient 0.63, p<0.001. The most frequent T/QRS baseline is 0.12.

conclusionThe orientation of the fetal electrical heart axis and accordingly the height of the initial T/QRS baseline should be taken into account in fetal monitoring with ST analysis.

Indexed as

Fetal MonitoringAdolescentAdultCesarean SectionElectrocardiographyFemaleFetal BloodFetal DiseasesGestational AgeHeart Rate, FetalHumansHydrogen-Ion ConcentrationLabor, ObstetricPregnancyYoung Adult

Identifiers

PMID28410419
PMCPMC5391944
OpenAlexW2607444309

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.