ArticleEye & contact lens2018
Evaluated Conjunctival Blood Flow Velocity in Daily Contact Lens Wearers.
Article in Eye & contact lens, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- An LSPR-Active AuNP-Silicone Hydrogel Contact Lens for Continuous Ocular Strain Sensing: From Engineering Design to In Vivo Validation.Biosensors · 2026Article
- Vascular characteristics and haemodynamics of severe and mild pterygium: a quantitative analysis.Annals of medicine · 2025Observational
- Investigating the vascular structure of the conjunctiva in patients using spherical mini-scleral contact lenses utilizing OCT-A imaging.Scientific reports · 2025Article
- Dynamic Changes of Ocular Surface in First-Time Contact Lens Wearers and the Effective Factors of Contact Lens Discomfort.Frontiers in medicine · 2022Article
- Progress of Bulbar Conjunctival Microcirculation Alterations in the Diagnosis of Ocular Diseases.Disease markers · 2022Review
- Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers.Eye and vision (London, England) · 2019Article
- A review of functional slit lamp biomicroscopy.Eye and vision (London, England) · 2019Review
- Microcirculation in the conjunctiva and retina in healthy subjects.Eye and vision (London, England) · 2019Article
- Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.Investigative ophthalmology & visual science · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveThis study examined conjunctival microvasculature development in long-term habitual contact lens (HCL) wearers after a night of sleep.
methodsTwenty HCL wearers (15 women and 5 men, aged 28.6±6.9 years, mean age±standard deviation) who had worn contact lenses on a daily basis for at least 3 years and 40 noncontact lens (NCL) wearers (23 women and 17 men, aged 36.5±6.6 years, mean age±standard deviation) participated in the study. A functional slitlamp biomicroscopy imaging system was used to image the temporal bulbar conjunctiva. Imaging was performed in the morning while the contact lens wearers were not wearing their lenses after a night of sleep. The conjunctival vessel diameters, blood flow velocities, and flow rates were measured. In addition, fractal analyses were performed to obtain the vessel network density (Dbox) and complexity (D0).
resultsThe average blood flow velocity in HCL wearers after a night of sleep was 0.59±0.19 mm/s, which was significantly higher than that in NCL wearers (0.48±0.17 mm/s, P<0.05). The microvessel network density and complexity levels (Dbox=1.64±0.05 and D0=1.71±0.05, respectively) in the HCL wearers were significantly higher than those in NCL wearers (Dbox=1.61±0.05 and D0=1.69±0.04, both P<0.05). The blood flow velocity was positively correlated with the duration of contact lens wear (r=0.46, P<0.05) and with the daily number of lens-wearing hours (r=0.49, P<0.05) in HCL wearers.
conclusionsThis study identified microvascular alterations in the conjunctiva in response to daily contact lens wear after a night of sleep in long-term daily contact lens wearers. The unrecovered changes may indicate that para-inflammation occurs on ocular surfaces because of contact lens wear and that overnight sleeping with no lenses may not sufficiently restore the ocular surface to an intact state.
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