SynthesisOncotarget2017
Impact of perioperative blood transfusion on clinical outcomes in patients with colorectal liver metastasis after hepatectomy: a meta-analysis.
Synthesis in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Perioperative outcomes of utilizing infrahepatic inferior vena cava clamping and Pringle maneuver during hepatectomy: a meta-analysis.Langenbeck's archives of surgery · 2024Pooled it
- Pooled it
- Systematic Review and Meta-Analysis on the Role of Perioperative Blood Transfusion in Patients Undergoing Radical Cystectomy for Urothelial Carcinoma.Bladder cancer (Amsterdam, Netherlands) · 2022Pooled it
- Trial
- High inappropriate red blood cell transfusion rate despite low overall use: a real-world multicenter study in 43 Spanish hospitals.Frontiers in medicine · 2026Article
- Perioperative Blood Transfusions and Cancer Progression: A Narrative Review.Current oncology reports · 2024Review
- The application of a single-hand-operated hepatic pedicle clamping clamp in laparoscopic hepatectomy.Langenbeck's archives of surgery · 2024Article
- Volumetric Remodeling of the Left Liver After Right Hepatectomy: Analysis of Factors Predicting Degree of Hypertrophy and Post-hepatectomy Liver Failure.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- A systematic review and meta-analysis of blood transfusion rates during liver resection by country.Annals of surgical treatment and research · 2023Article
- The Pringle maneuver in the modern era: A review of techniques for hepatic inflow occlusion in minimally invasive liver resection.Annals of hepato-biliary-pancreatic surgery · 2023Review
- Generating real-world evidence compatible with evidence from randomized controlled trials: a novel observational study design applicable to surgical transfusion research.BMC medical research methodology · 2022Observational
- Impact of perioperative blood transfusions on postoperative renal function and survival after resection of colorectal liver metastases.World journal of surgical oncology · 2022Article
- Prognostic Impact of Pedicle Clamping during Liver Resection for Colorectal Metastases.Cancers · 2020Article
- Does laparoscopic liver resection for colorectal liver metastases provide a true survival benefit compared with open liver resection?Hepatobiliary surgery and nutrition · 2020Article
- Anatomical Versus Nonanatomical Resection for Colorectal Liver Metastasis.World journal of surgery · 2020Article
- Guidelines on the intraoperative transfusion of red blood cells: a protocol for systematic review.BMJ open · 2019Article
- Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study.World journal of surgery · 2019Article
- Impact of perioperative transfusion in patients undergoing resection of colorectal cancer liver metastases: A population-based study.World journal of clinical cases · 2019Article
- Proposal of Two Prognostic Models for the Prediction of 10-Year Survival after Liver Resection for Colorectal Metastases.HPB surgery : a world journal of hepatic, pancreatic and biliary surgery · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerioperative blood transfusion may be associated with negative clinical outcomes in oncological surgery. A meta-analysis of published studies was conducted to evaluate the impact of blood transfusion on short- and long-term outcomes following liver resection of colorectal liver metastasis (CLM). MATERIALS AND
methodsA systematic search was performed to identify relevant articles. Data were pooled for meta-analysis using Review Manager version 5.3.
resultsTwenty-five observational studies containing 10621 patients were subjected to the analysis. Compared with non-transfused patients, transfused patients experienced higher overall morbidity (odds ratio [OR], 1.98; 95% confidence intervals [CI] =1.49-2.33), more major complications (OR, 2.12; 95% CI =1.26-3.58), higher mortality (OR, 4.13; 95% CI =1.96-8.72), and longer length of hospital stay (weighted mean difference, 4.43; 95% CI =1.15-7.69). Transfusion was associated with reduced overall survival (risk ratio [RR], 1.24, 95% CI =1.11-1.38) and disease-free survival (RR, 1.38, 95% CI=1.23-1.56).
conclusionPerioperative blood transfusion has a detrimental impact on the clinical outcomes of patients undergoing CLM resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.