ArticleJMIR cancer2016
The Effects of Physical Activity on Health and Quality of Life in Adolescent Cancer Survivors: A Systematic Review.
Article in JMIR cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- The effect of physical activity on health-related outcomes in children and adolescents with cancer: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Exercise intervention for children with acute leukemia: a best evidence summary.Frontiers in pediatrics · 2026Pooled it
- Effect of Physical Activity on Health-Related Quality of Life among Cancer Patients and Survivors: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2024Pooled it
- Wearables for Measuring the Physical Activity and Sedentary Behavior of Patients With Axial Spondyloarthritis: Systematic Review.JMIR mHealth and uHealth · 2022Pooled it
- Use of active video games with or without videoconferencing on health outcomes in adolescent and young adult cancer survivors: a systematic review.Journal of cancer survivorship : research and practice · 2022Pooled it
- Physical and functional performance assessment in pediatric oncology: a systematic review.Pediatric research · 2022Pooled it
- Association between physical activity and risk of prevalent psoriasis: A MOOSE-compliant meta-analysis.Medicine · 2018Pooled it
- Effects of Exercise Intervention on Quality of Life in Adolescent and Young Adult Cancer Patients and Survivors: A Meta-Analysis.Integrative cancer therapiesPooled it
- Intelligent physical activity versus modified behavioral activation in adolescent and young adult cancer patients with psychological distress: A randomized, controlled pilot trial.Cancer medicine · 2023Trial
- Efficacy of Mobile Instant Messaging-Delivered Brief Motivational Interviewing for Parents to Promote Physical Activity in Pediatric Cancer Survivors: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Navigating ethical challenges in the FORTEe randomised controlled trial: a multi-centre staff survey on exercise intervention for children and adolescents undergoing cancer treatment.BMC medical ethics · 2026Article
- Parent and child physical activity as possible predictors of quality of life in pediatric brain tumor patients: a dyadic analysis.Health psychology and behavioral medicine · 2025Article
- Telemedicine-based adapted physical activity programs for pediatric oncology patients in active oncological care: a feasibility study.Frontiers in oncology · 2025Article
- Observational
- Healthcare providers' promotion of physical activity among child and adolescent cancer survivors: strategies and challenges.Journal of cancer survivorship : research and practice · 2023Article
- Chronic pain in children and adolescents diagnosed with cancer: the challenge of mitigating the pain and the potential of integrating exercise into pain management.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- Safety, Feasibility and Efficacy of LokomatCancers · 2023Article
- Article
- Radiotherapy-Related Fatigue Associated Impairments in Lung Cancer Survivors during COVID-19 Voluntary Isolation.Healthcare (Basel, Switzerland) · 2022Article
- Synthesizing the literature on physical activity among children and adolescents affected by cancer: evidence for the international Pediatric Oncology Exercise Guidelines (iPOEG).Translational behavioral medicine · 2021Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are numerous published controlled trials assessing the safety and the benefits of physical activity (PA) for child and adult cancer survivors. However, trials exclusively comprised of adolescent cancer survivors aged 13-19 years, who may experience different health and quality of life (QOL) effects as a function of their developmental status, are lacking. Rather, some trials have included both adolescent and child cancer survivors together.
objectiveThe aim of this systematic review was to synthesize the findings from randomized controlled trails (RCTs) and controlled clinical trials (CCTs) investigating the effects of PA on health and QOL outcomes in samples comprised of >50% adolescent cancer survivors to summarize the current state of evidence, identify knowledge gaps, and highlight areas in need of additional research within this population.
methodsUsing a search strategy developed for this review, 10 electronic databases were searched for RCTs and CCTs that reported on the effects of PA on at least 1 health and/or QOL outcome in samples comprised of >50% adolescent cancer survivors.
resultsFrom the 2249 articles identified, 2 CCTs met the predetermined eligibility criteria and were included in this review. Combined, 28 adolescents (of 41 participants) who were receiving active treatment participated in the 2 studies reviewed. A total of 4 health and QOL outcomes (ie, bone mass, fatigue, grip strength, QOL) were assessed pre- and post-PA intervention.
conclusionsOn the basis of the 2 studies reviewed, PA appears to be safe and feasible. PA also shows promise to mitigate reductions in bone mass and might be a viable strategy to improve fatigue, grip strength, and QOL. High-quality controlled trials with larger samples exclusively comprised of adolescent cancer survivors that assess a wide range of outcomes are needed to determine the effects of PA on health and QOL outcomes in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.